J024-0193 Screening compound: 11-(4-methoxyphenyl)-N~10~,3,3-trimethyl-1-oxo-1,2,3,4,5,11-hexahydro-10H-dibenzo[b,e][1,4]diazepine-10-carboxamide

J024-0193 Screening compound: 11-(4-methoxyphenyl)-N~10~,3,3-trimethyl-1-oxo-1,2,3,4,5,11-hexahydro-10H-dibenzo[b,e][1,4]diazepine-10-carboxamide
J024-0193 Screening compound: 11-(4-methoxyphenyl)-N~10~,3,3-trimethyl-1-oxo-1,2,3,4,5,11-hexahydro-10H-dibenzo[b,e][1,4]diazepine-10-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound J024-0193
11-(4-methoxyphenyl)-N~10~,3,3-trimethyl-1-oxo-1,2,3,4,5,11-hexahydro-10H-dibenzo[b,e][1,4]diazepine-10-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J024-0193

Molecular Formula

C24H27N3O3 (C24 H27 N3 O3)

Compound Name

11-(4-methoxyphenyl)-N~10~,3,3-trimethyl-1-oxo-1,2,3,4,5,11-hexahydro-10H-dibenzo[b,e][1,4]diazepine-10-carboxamide

IUPAC name

10-(4-methoxyphenyl)-N1414-trimethyl-12-oxo-29-diazatricyclo[9.4.0.0^{38}]pentadeca-1(11)3(8)46-tetraene-9-carboxamide

SMILES

CC(C)(C1)CC(Nc(cccc2)c2N(C2c(cc3)ccc3OC)C(NC)=O)=C2C1=O

InChI

InChI=1S/C24H27N3O3/c1-24(2)13-18-21(20(28)14-24)22(15-9-11-16(30-4)12-10-15)27(23(29)25-3)19-8-6-5-7-17(19)26-18/h5-12,22,26H,13-14H2,1-4H3,(H,25,29)/t22-/m0/s1

InChI Key

RNLOLNCSTMKDDI-QFIPXVFZSA-N

MDL Number (MFCD)

MFCD18912705

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

405.5

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.186

Distribution Coefficient, logD

4.164

Water Solubility, LogSw

-4.38

Polar Surface Area

57.273

Acid Dissociation Constant (pKa)

8.68

Base Dissociation Constant (pKb)

-0.91

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

33.30

J024-0193 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with J024-0193 chemical compound. It will be published here after verification.

Frequently Asked Questions

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What is the minimum amount of J024-0193 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J024-0193
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J024-0193
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J024-0193 available by request