J024-0243 Screening compound: 11-(2-furyl)-3,3-dimethyl-N~10~-(2-methylphenyl)-1-oxo-1,2,3,4,5,11-hexahydro-10H-dibenzo[b,e][1,4]diazepine-10-carboxamide

J024-0243 Screening compound: 11-(2-furyl)-3,3-dimethyl-N~10~-(2-methylphenyl)-1-oxo-1,2,3,4,5,11-hexahydro-10H-dibenzo[b,e][1,4]diazepine-10-carboxamide
J024-0243 Screening compound: 11-(2-furyl)-3,3-dimethyl-N~10~-(2-methylphenyl)-1-oxo-1,2,3,4,5,11-hexahydro-10H-dibenzo[b,e][1,4]diazepine-10-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound J024-0243
11-(2-furyl)-3,3-dimethyl-N~10~-(2-methylphenyl)-1-oxo-1,2,3,4,5,11-hexahydro-10H-dibenzo[b,e][1,4]diazepine-10-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J024-0243

Molecular Formula

C27H27N3O3 (C27 H27 N3 O3)

Compound Name

11-(2-furyl)-3,3-dimethyl-N~10~-(2-methylphenyl)-1-oxo-1,2,3,4,5,11-hexahydro-10H-dibenzo[b,e][1,4]diazepine-10-carboxamide

IUPAC name

10-(furan-2-yl)-1414-dimethyl-N-(2-methylphenyl)-12-oxo-29-diazatricyclo[9.4.0.0^{38}]pentadeca-1(11)3(8)46-tetraene-9-carboxamide

SMILES

CC(C)(C1)CC(Nc(cccc2)c2N(C2c3ccco3)C(Nc3c(C)cccc3)=O)=C2C1=O

InChI

InChI=1S/C27H27N3O3/c1-17-9-4-5-10-18(17)29-26(32)30-21-12-7-6-11-19(21)28-20-15-27(2,3)16-22(31)24(20)25(30)23-13-8-14-33-23/h4-14,25,28H,15-16H2,1-3H3,(H,29,32)/t25-/m0/s1

InChI Key

DORAZSQIUSYLDV-VWLOTQADSA-N

MDL Number (MFCD)

MFCD15078649

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

441.53

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.365

Distribution Coefficient, logD

5.225

Water Solubility, LogSw

-5.35

Polar Surface Area

55.866

Acid Dissociation Constant (pKa)

7.82

Base Dissociation Constant (pKb)

0.28

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

25.90

J024-0243 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Protein-Protein Interaction Library (218420 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with J024-0243 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound J024-0243?
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What is the minimum amount of J024-0243 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J024-0243
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J024-0243
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J024-0243 available by request