J024-0760 Screening compound: 10-[(3,4-dimethylphenyl)sulfonyl]-11-(2-thienyl)-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one

J024-0760 Screening compound: 10-[(3,4-dimethylphenyl)sulfonyl]-11-(2-thienyl)-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one
J024-0760 Screening compound: 10-[(3,4-dimethylphenyl)sulfonyl]-11-(2-thienyl)-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound J024-0760
10-[(3,4-dimethylphenyl)sulfonyl]-11-(2-thienyl)-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J024-0760

Molecular Formula

C25H24N2O3S2 (C25 H24 N2 O3 S2)

Compound Name

10-[(3,4-dimethylphenyl)sulfonyl]-11-(2-thienyl)-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one

IUPAC name

9-(34-dimethylbenzenesulfonyl)-10-(thiophen-2-yl)-29-diazatricyclo[9.4.0.0^{38}]pentadeca-1(11)3(8)46-tetraen-12-one

SMILES

Cc(cc1)c(C)cc1S(N(C1c2cccs2)c(cccc2)c2NC(CCC2)=C1C2=O)(=O)=O

InChI

InChI=1S/C25H24N2O3S2/c1-16-12-13-18(15-17(16)2)32(29,30)27-21-9-4-3-7-19(21)26-20-8-5-10-22(28)24(20)25(27)23-11-6-14-31-23/h3-4,6-7,9,11-15,25-26H,5,8,10H2,1-2H3/t25-/m0/s1

InChI Key

CZHFMWUFRRJDQT-VWLOTQADSA-N

MDL Number (MFCD)

MFCD13969221

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

464.61

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.780

Distribution Coefficient, logD

5.753

Water Solubility, LogSw

-5.38

Polar Surface Area

56.799

Acid Dissociation Constant (pKa)

8.59

Base Dissociation Constant (pKb)

-3.08

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

24.00

J024-0760 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with J024-0760 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound J024-0760?
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What is the minimum amount of J024-0760 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J024-0760
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J024-0760
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J024-0760 available by request