J026-0840 Screening compound: N-cyclohexyl-2-[1-(2-methoxyphenyl)-5,7-dimethyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]acetamide

J026-0840 Screening compound: N-cyclohexyl-2-[1-(2-methoxyphenyl)-5,7-dimethyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]acetamide
J026-0840 Screening compound: N-cyclohexyl-2-[1-(2-methoxyphenyl)-5,7-dimethyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound J026-0840
N-cyclohexyl-2-[1-(2-methoxyphenyl)-5,7-dimethyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J026-0840

Molecular Formula

C24H28N4O4 (C24 H28 N4 O4)

Compound Name

N-cyclohexyl-2-[1-(2-methoxyphenyl)-5,7-dimethyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]acetamide

IUPAC name

N-cyclohexyl-2-[1-(2-methoxyphenyl)-57-dimethyl-24-dioxo-1H2H3H4H-pyrido[23-d]pyrimidin-3-yl]acetamide

SMILES

Cc(cc(C)nc1N(c(cccc2)c2OC)C(N2CC(NC3CCCCC3)=O)=O)c1C2=O

InChI

InChI=1S/C24H28N4O4/c1-15-13-16(2)25-22-21(15)23(30)27(14-20(29)26-17-9-5-4-6-10-17)24(31)28(22)18-11-7-8-12-19(18)32-3/h7-8,11-13,17H,4-6,9-10,14H2,1-3H3,(H,26,29)

InChI Key

SPXHQFHEWDCTQS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27219651

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

436.51

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.421

Distribution Coefficient, logD

3.417

Water Solubility, LogSw

-3.88

Polar Surface Area

71.887

Acid Dissociation Constant (pKa)

16.21

Base Dissociation Constant (pKb)

5.36

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.70

J026-0840 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system

References: we are preparing a list of scientific research reports with J026-0840 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound J026-0840?
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What is the minimum amount of J026-0840 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J026-0840
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J026-0840
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J026-0840 available by request