J026-2094 Screening compound: methyl 7-cyclopropyl-3-{[(2-fluorophenyl)carbamoyl]methyl}-2,4-dioxo-1-phenyl-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-5-carboxylate

J026-2094 Screening compound: methyl 7-cyclopropyl-3-{[(2-fluorophenyl)carbamoyl]methyl}-2,4-dioxo-1-phenyl-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-5-carboxylate
J026-2094 Screening compound: methyl 7-cyclopropyl-3-{[(2-fluorophenyl)carbamoyl]methyl}-2,4-dioxo-1-phenyl-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-5-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound J026-2094
methyl 7-cyclopropyl-3-{[(2-fluorophenyl)carbamoyl]methyl}-2,4-dioxo-1-phenyl-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-5-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J026-2094

Molecular Formula

C26H21FN4O5 (C26 H21 FN4 O5)

Compound Name

methyl 7-cyclopropyl-3-{[(2-fluorophenyl)carbamoyl]methyl}-2,4-dioxo-1-phenyl-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-5-carboxylate

IUPAC name

methyl 7-cyclopropyl-3-{[(2-fluorophenyl)carbamoyl]methyl}-24-dioxo-1-phenyl-1H2H3H4H-pyrido[23-d]pyrimidine-5-carboxylate

SMILES

COC(c1cc(C2CC2)nc(N(c2ccccc2)C(N2CC(Nc(cccc3)c3F)=O)=O)c1C2=O)=O

InChI

InChI=1S/C26H21FN4O5/c1-36-25(34)17-13-20(15-11-12-15)29-23-22(17)24(33)30(26(35)31(23)16-7-3-2-4-8-16)14-21(32)28-19-10-6-5-9-18(19)27/h2-10,13,15H,11-12,14H2,1H3,(H,28,32)

InChI Key

YYLGBZXYYQTNCO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09779750

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

488.48

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.929

Distribution Coefficient, logD

3.929

Water Solubility, LogSw

-4.20

Polar Surface Area

84.431

Acid Dissociation Constant (pKa)

11.37

Base Dissociation Constant (pKb)

3.90

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.20

J026-2094 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with J026-2094 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound J026-2094?
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What is the minimum amount of J026-2094 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J026-2094
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J026-2094
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J026-2094 available by request