J026-2229 Screening compound: methyl 1-(2-methoxyphenyl)-7-methyl-2,4-dioxo-3-[(pyridin-2-yl)methyl]-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-5-carboxylate

J026-2229 Screening compound: methyl 1-(2-methoxyphenyl)-7-methyl-2,4-dioxo-3-[(pyridin-2-yl)methyl]-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-5-carboxylate
J026-2229 Screening compound: methyl 1-(2-methoxyphenyl)-7-methyl-2,4-dioxo-3-[(pyridin-2-yl)methyl]-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-5-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound J026-2229
methyl 1-(2-methoxyphenyl)-7-methyl-2,4-dioxo-3-[(pyridin-2-yl)methyl]-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-5-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J026-2229

Molecular Formula

C23H20N4O5 (C23 H20 N4 O5)

Compound Name

methyl 1-(2-methoxyphenyl)-7-methyl-2,4-dioxo-3-[(pyridin-2-yl)methyl]-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-5-carboxylate

IUPAC name

methyl 1-(2-methoxyphenyl)-7-methyl-24-dioxo-3-[(pyridin-2-yl)methyl]-1H2H3H4H-pyrido[23-d]pyrimidine-5-carboxylate

SMILES

Cc(nc1N(c(cccc2)c2OC)C(N2Cc3ncccc3)=O)cc(C(OC)=O)c1C2=O

InChI

InChI=1S/C23H20N4O5/c1-14-12-16(22(29)32-3)19-20(25-14)27(17-9-4-5-10-18(17)31-2)23(30)26(21(19)28)13-15-8-6-7-11-24-15/h4-12H,13H2,1-3H3

InChI Key

XFCHRNUEYGBPNV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09779725

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

432.44

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.636

Distribution Coefficient, logD

2.635

Water Solubility, LogSw

-3.01

Polar Surface Area

78.407

Acid Dissociation Constant (pKa)

28.25

Base Dissociation Constant (pKb)

4.22

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.40

J026-2229 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases
Agro:
  • Agro

References: we are preparing a list of scientific research reports with J026-2229 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound J026-2229?
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What is the minimum amount of J026-2229 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J026-2229
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J026-2229
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J026-2229 available by request