J026-2238 Screening compound: methyl 3-[(2,5-dimethylphenyl)methyl]-1-(2-methoxyphenyl)-7-methyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-5-carboxylate

J026-2238 Screening compound: methyl 3-[(2,5-dimethylphenyl)methyl]-1-(2-methoxyphenyl)-7-methyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-5-carboxylate
J026-2238 Screening compound: methyl 3-[(2,5-dimethylphenyl)methyl]-1-(2-methoxyphenyl)-7-methyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-5-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound J026-2238
methyl 3-[(2,5-dimethylphenyl)methyl]-1-(2-methoxyphenyl)-7-methyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-5-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J026-2238

Molecular Formula

C26H25N3O5 (C26 H25 N3 O5)

Compound Name

methyl 3-[(2,5-dimethylphenyl)methyl]-1-(2-methoxyphenyl)-7-methyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-5-carboxylate

IUPAC name

methyl 3-[(25-dimethylphenyl)methyl]-1-(2-methoxyphenyl)-7-methyl-24-dioxo-1H2H3H4H-pyrido[23-d]pyrimidine-5-carboxylate

SMILES

Cc1cc(CN(C(c(c(N2c(cccc3)c3OC)nc(C)c3)c3C(OC)=O)=O)C2=O)c(C)cc1

InChI

InChI=1S/C26H25N3O5/c1-15-10-11-16(2)18(12-15)14-28-24(30)22-19(25(31)34-5)13-17(3)27-23(22)29(26(28)32)20-8-6-7-9-21(20)33-4/h6-13H,14H2,1-5H3

InChI Key

YLBWXNPMHYKNDM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09779694

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

459.5

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.968

Distribution Coefficient, logD

4.968

Water Solubility, LogSw

-4.75

Polar Surface Area

68.864

Acid Dissociation Constant (pKa)

26.64

Base Dissociation Constant (pKb)

4.22

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.10

J026-2238 in Drug Discovery

Included in Screening Libraries

GABA Library (7115 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Eye
Targets:
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with J026-2238 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound J026-2238?
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What is the minimum amount of J026-2238 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J026-2238
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J026-2238
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J026-2238 available by request