J026-2298 Screening compound: methyl 7-cyclopropyl-1-(2-methoxyphenyl)-3-[(4-methoxyphenyl)methyl]-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-5-carboxylate

J026-2298 Screening compound: methyl 7-cyclopropyl-1-(2-methoxyphenyl)-3-[(4-methoxyphenyl)methyl]-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-5-carboxylate
J026-2298 Screening compound: methyl 7-cyclopropyl-1-(2-methoxyphenyl)-3-[(4-methoxyphenyl)methyl]-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-5-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound J026-2298
methyl 7-cyclopropyl-1-(2-methoxyphenyl)-3-[(4-methoxyphenyl)methyl]-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-5-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J026-2298

Molecular Formula

C27H25N3O6 (C27 H25 N3 O6)

Compound Name

methyl 7-cyclopropyl-1-(2-methoxyphenyl)-3-[(4-methoxyphenyl)methyl]-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-5-carboxylate

IUPAC name

methyl 7-cyclopropyl-1-(2-methoxyphenyl)-3-[(4-methoxyphenyl)methyl]-24-dioxo-1H2H3H4H-pyrido[23-d]pyrimidine-5-carboxylate

SMILES

COC(c(cc(C1CC1)nc1N(c(cccc2)c2OC)C(N2Cc(cc3)ccc3OC)=O)c1C2=O)=O

InChI

InChI=1S/C27H25N3O6/c1-34-18-12-8-16(9-13-18)15-29-25(31)23-19(26(32)36-3)14-20(17-10-11-17)28-24(23)30(27(29)33)21-6-4-5-7-22(21)35-2/h4-9,12-14,17H,10-11,15H2,1-3H3

InChI Key

SRHPTISMAOYIAU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09779669

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

487.51

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

4.706

Distribution Coefficient, logD

4.695

Water Solubility, LogSw

-4.63

Polar Surface Area

76.853

Acid Dissociation Constant (pKa)

23.57

Base Dissociation Constant (pKb)

5.82

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.90

J026-2298 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

GABA Library (7115 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Eye
Targets:
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with J026-2298 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound J026-2298?
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What is the minimum amount of J026-2298 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J026-2298
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J026-2298
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J026-2298 available by request