J026-2976 Screening compound: 2-[7-methyl-2,4-dioxo-1-phenyl-5-(piperidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]-N-propylacetamide

J026-2976 Screening compound: 2-[7-methyl-2,4-dioxo-1-phenyl-5-(piperidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]-N-propylacetamide
J026-2976 Screening compound: 2-[7-methyl-2,4-dioxo-1-phenyl-5-(piperidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]-N-propylacetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound J026-2976
2-[7-methyl-2,4-dioxo-1-phenyl-5-(piperidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]-N-propylacetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J026-2976

Molecular Formula

C25H29N5O4 (C25 H29 N5 O4)

Compound Name

2-[7-methyl-2,4-dioxo-1-phenyl-5-(piperidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]-N-propylacetamide

IUPAC name

2-[7-methyl-24-dioxo-1-phenyl-5-(piperidine-1-carbonyl)-1H2H3H4H-pyrido[23-d]pyrimidin-3-yl]-N-propylacetamide

SMILES

CCCNC(CN(C(c(c(N1c2ccccc2)nc(C)c2)c2C(N2CCCCC2)=O)=O)C1=O)=O

InChI

InChI=1S/C25H29N5O4/c1-3-12-26-20(31)16-29-24(33)21-19(23(32)28-13-8-5-9-14-28)15-17(2)27-22(21)30(25(29)34)18-10-6-4-7-11-18/h4,6-7,10-11,15H,3,5,8-9,12-14,16H2,1-2H3,(H,26,31)

InChI Key

KLKYBUIYFROKHK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27219756

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

463.54

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.250

Distribution Coefficient, logD

2.250

Water Solubility, LogSw

-3.11

Polar Surface Area

81.593

Acid Dissociation Constant (pKa)

16.25

Base Dissociation Constant (pKb)

2.90

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

J026-2976 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with J026-2976 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound J026-2976?
Check Price and Availability of J026-2976, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of J026-2976 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J026-2976
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J026-2976
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J026-2976 available by request