J026-2977 Screening compound: 3-[(3-fluorophenyl)methyl]-7-methyl-1-phenyl-5-(piperidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-2,4-dione

J026-2977 Screening compound: 3-[(3-fluorophenyl)methyl]-7-methyl-1-phenyl-5-(piperidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-2,4-dione
J026-2977 Screening compound: 3-[(3-fluorophenyl)methyl]-7-methyl-1-phenyl-5-(piperidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-2,4-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound J026-2977
3-[(3-fluorophenyl)methyl]-7-methyl-1-phenyl-5-(piperidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-2,4-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J026-2977

Molecular Formula

C27H25FN4O3 (C27 H25 FN4 O3)

Compound Name

3-[(3-fluorophenyl)methyl]-7-methyl-1-phenyl-5-(piperidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-2,4-dione

IUPAC name

3-[(3-fluorophenyl)methyl]-7-methyl-1-phenyl-5-(piperidine-1-carbonyl)-1H2H3H4H-pyrido[23-d]pyrimidine-24-dione

SMILES

Cc(cc1C(N2CCCCC2)=O)nc(N(c2ccccc2)C(N2Cc3cccc(F)c3)=O)c1C2=O

InChI

InChI=1S/C27H25FN4O3/c1-18-15-22(25(33)30-13-6-3-7-14-30)23-24(29-18)32(21-11-4-2-5-12-21)27(35)31(26(23)34)17-19-9-8-10-20(28)16-19/h2,4-5,8-12,15-16H,3,6-7,13-14,17H2,1H3

InChI Key

GEEUIHUZHASJNF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27219757

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

472.52

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.322

Distribution Coefficient, logD

4.322

Water Solubility, LogSw

-4.48

Polar Surface Area

57.009

Acid Dissociation Constant (pKa)

26.61

Base Dissociation Constant (pKb)

3.28

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.90

J026-2977 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with J026-2977 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound J026-2977?
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What is the minimum amount of J026-2977 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J026-2977
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J026-2977
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J026-2977 available by request