J026-2993 Screening compound: 2-[7-methyl-2,4-dioxo-1-phenyl-5-(piperidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]-N-phenylacetamide

J026-2993 Screening compound: 2-[7-methyl-2,4-dioxo-1-phenyl-5-(piperidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]-N-phenylacetamide
J026-2993 Screening compound: 2-[7-methyl-2,4-dioxo-1-phenyl-5-(piperidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]-N-phenylacetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound J026-2993
2-[7-methyl-2,4-dioxo-1-phenyl-5-(piperidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]-N-phenylacetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J026-2993

Molecular Formula

C28H27N5O4 (C28 H27 N5 O4)

Compound Name

2-[7-methyl-2,4-dioxo-1-phenyl-5-(piperidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]-N-phenylacetamide

IUPAC name

2-[7-methyl-24-dioxo-1-phenyl-5-(piperidine-1-carbonyl)-1H2H3H4H-pyrido[23-d]pyrimidin-3-yl]-N-phenylacetamide

SMILES

Cc(nc1N(c2ccccc2)C(N2CC(Nc3ccccc3)=O)=O)cc(C(N3CCCCC3)=O)c1C2=O

InChI

InChI=1S/C28H27N5O4/c1-19-17-22(26(35)31-15-9-4-10-16-31)24-25(29-19)33(21-13-7-3-8-14-21)28(37)32(27(24)36)18-23(34)30-20-11-5-2-6-12-20/h2-3,5-8,11-14,17H,4,9-10,15-16,18H2,1H3,(H,30,34)

InChI Key

OTSZBVLUMDZRMR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09780394

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

497.55

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.414

Distribution Coefficient, logD

3.414

Water Solubility, LogSw

-3.76

Polar Surface Area

80.158

Acid Dissociation Constant (pKa)

13.25

Base Dissociation Constant (pKb)

2.90

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

J026-2993 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic
  • PPI modulators

References: we are preparing a list of scientific research reports with J026-2993 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound J026-2993?
Check Price and Availability of J026-2993, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of J026-2993 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J026-2993
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J026-2993
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J026-2993 available by request