J026-3266 Screening compound: N-tert-butyl-2-[7-methyl-2,4-dioxo-1-phenyl-5-(pyrrolidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]acetamide

J026-3266 Screening compound: N-tert-butyl-2-[7-methyl-2,4-dioxo-1-phenyl-5-(pyrrolidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]acetamide
J026-3266 Screening compound: N-tert-butyl-2-[7-methyl-2,4-dioxo-1-phenyl-5-(pyrrolidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound J026-3266
N-tert-butyl-2-[7-methyl-2,4-dioxo-1-phenyl-5-(pyrrolidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J026-3266

Molecular Formula

C25H29N5O4 (C25 H29 N5 O4)

Compound Name

N-tert-butyl-2-[7-methyl-2,4-dioxo-1-phenyl-5-(pyrrolidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]acetamide

IUPAC name

N-tert-butyl-2-[7-methyl-24-dioxo-1-phenyl-5-(pyrrolidine-1-carbonyl)-1H2H3H4H-pyrido[23-d]pyrimidin-3-yl]acetamide

SMILES

CC(C)(C)NC(CN(C(c(c(N1c2ccccc2)nc(C)c2)c2C(N2CCCC2)=O)=O)C1=O)=O

InChI

InChI=1S/C25H29N5O4/c1-16-14-18(22(32)28-12-8-9-13-28)20-21(26-16)30(17-10-6-5-7-11-17)24(34)29(23(20)33)15-19(31)27-25(2,3)4/h5-7,10-11,14H,8-9,12-13,15H2,1-4H3,(H,27,31)

InChI Key

TZUPEYAIBJRLLE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09780323

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

463.54

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.729

Distribution Coefficient, logD

2.728

Water Solubility, LogSw

-3.27

Polar Surface Area

80.942

Acid Dissociation Constant (pKa)

15.80

Base Dissociation Constant (pKb)

4.07

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

J026-3266 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with J026-3266 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound J026-3266?
Check Price and Availability of J026-3266, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of J026-3266 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J026-3266
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J026-3266
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J026-3266 available by request