J026-3275 Screening compound: N-cyclopentyl-2-[7-methyl-2,4-dioxo-1-phenyl-5-(pyrrolidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]acetamide

J026-3275 Screening compound: N-cyclopentyl-2-[7-methyl-2,4-dioxo-1-phenyl-5-(pyrrolidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]acetamide
J026-3275 Screening compound: N-cyclopentyl-2-[7-methyl-2,4-dioxo-1-phenyl-5-(pyrrolidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound J026-3275
N-cyclopentyl-2-[7-methyl-2,4-dioxo-1-phenyl-5-(pyrrolidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J026-3275

Molecular Formula

C26H29N5O4 (C26 H29 N5 O4)

Compound Name

N-cyclopentyl-2-[7-methyl-2,4-dioxo-1-phenyl-5-(pyrrolidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]acetamide

IUPAC name

N-cyclopentyl-2-[7-methyl-24-dioxo-1-phenyl-5-(pyrrolidine-1-carbonyl)-1H2H3H4H-pyrido[23-d]pyrimidin-3-yl]acetamide

SMILES

Cc(nc1N(c2ccccc2)C(N2CC(NC3CCCC3)=O)=O)cc(C(N3CCCC3)=O)c1C2=O

InChI

InChI=1S/C26H29N5O4/c1-17-15-20(24(33)29-13-7-8-14-29)22-23(27-17)31(19-11-3-2-4-12-19)26(35)30(25(22)34)16-21(32)28-18-9-5-6-10-18/h2-4,11-12,15,18H,5-10,13-14,16H2,1H3,(H,28,32)

InChI Key

ANNWOTRRMTVWEA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09780335

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

475.55

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.662

Distribution Coefficient, logD

2.662

Water Solubility, LogSw

-3.22

Polar Surface Area

81.938

Acid Dissociation Constant (pKa)

16.87

Base Dissociation Constant (pKb)

2.90

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.30

J026-3275 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anticancer Library (62698 compounds)

Antiviral Library (67538 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Antiviral
  • Infections
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with J026-3275 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound J026-3275?
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What is the minimum amount of J026-3275 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J026-3275
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J026-3275
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J026-3275 available by request