J026-3576 Screening compound: N-(4-fluorophenyl)-N-methyl-2-{1,5,7-trimethyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl}acetamide

J026-3576 Screening compound: N-(4-fluorophenyl)-N-methyl-2-{1,5,7-trimethyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl}acetamide
J026-3576 Screening compound: N-(4-fluorophenyl)-N-methyl-2-{1,5,7-trimethyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound J026-3576
N-(4-fluorophenyl)-N-methyl-2-{1,5,7-trimethyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J026-3576

Molecular Formula

C19H19FN4O3 (C19 H19 FN4 O3)

Compound Name

N-(4-fluorophenyl)-N-methyl-2-{1,5,7-trimethyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl}acetamide

IUPAC name

N-(4-fluorophenyl)-N-methyl-2-{157-trimethyl-24-dioxo-1H2H3H4H-pyrido[23-d]pyrimidin-3-yl}acetamide

SMILES

Cc1cc(C)nc(N(C)C(N2CC(N(C)c(cc3)ccc3F)=O)=O)c1C2=O

InChI

InChI=1S/C19H19FN4O3/c1-11-9-12(2)21-17-16(11)18(26)24(19(27)23(17)4)10-15(25)22(3)14-7-5-13(20)6-8-14/h5-9H,10H2,1-4H3

InChI Key

GJSQEBDMXYITBL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD12965521

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

370.38

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.855

Distribution Coefficient, logD

1.855

Water Solubility, LogSw

-2.31

Polar Surface Area

56.122

Acid Dissociation Constant (pKa)

20.18

Base Dissociation Constant (pKb)

3.78

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.30

J026-3576 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with J026-3576 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound J026-3576?
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What is the minimum amount of J026-3576 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J026-3576
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J026-3576
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J026-3576 available by request