J026-3833 Screening compound: methyl 1,7-dimethyl-2,4-dioxo-3-[(phenylcarbamoyl)methyl]-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-5-carboxylate

J026-3833 Screening compound: methyl 1,7-dimethyl-2,4-dioxo-3-[(phenylcarbamoyl)methyl]-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-5-carboxylate
J026-3833 Screening compound: methyl 1,7-dimethyl-2,4-dioxo-3-[(phenylcarbamoyl)methyl]-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-5-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound J026-3833
methyl 1,7-dimethyl-2,4-dioxo-3-[(phenylcarbamoyl)methyl]-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-5-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J026-3833

Molecular Formula

C19H18N4O5 (C19 H18 N4 O5)

Compound Name

methyl 1,7-dimethyl-2,4-dioxo-3-[(phenylcarbamoyl)methyl]-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-5-carboxylate

IUPAC name

methyl 17-dimethyl-24-dioxo-3-[(phenylcarbamoyl)methyl]-1H2H3H4H-pyrido[23-d]pyrimidine-5-carboxylate

SMILES

Cc(cc1C(OC)=O)nc(N(C)C(N2CC(Nc3ccccc3)=O)=O)c1C2=O

InChI

InChI=1S/C19H18N4O5/c1-11-9-13(18(26)28-3)15-16(20-11)22(2)19(27)23(17(15)25)10-14(24)21-12-7-5-4-6-8-12/h4-9H,10H2,1-3H3,(H,21,24)

InChI Key

HEROTWWEOUWGCX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09788507

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

382.38

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.043

Distribution Coefficient, logD

2.043

Water Solubility, LogSw

-3.22

Polar Surface Area

85.332

Acid Dissociation Constant (pKa)

13.16

Base Dissociation Constant (pKb)

2.27

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.10

J026-3833 in Drug Discovery

Included in Screening Libraries

Chelators targeting matrix metalloproteinases library (8930 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with J026-3833 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound J026-3833?
Check Price and Availability of J026-3833, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of J026-3833 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J026-3833
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J026-3833
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J026-3833 available by request