J026-3968 Screening compound: ethyl 1,7-dimethyl-3-({5-methyl-2-[4-(propan-2-yl)phenyl]-1,3-oxazol-4-yl}methyl)-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-5-carboxylate

J026-3968 Screening compound: ethyl 1,7-dimethyl-3-({5-methyl-2-[4-(propan-2-yl)phenyl]-1,3-oxazol-4-yl}methyl)-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-5-carboxylate
J026-3968 Screening compound: ethyl 1,7-dimethyl-3-({5-methyl-2-[4-(propan-2-yl)phenyl]-1,3-oxazol-4-yl}methyl)-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-5-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound J026-3968
ethyl 1,7-dimethyl-3-({5-methyl-2-[4-(propan-2-yl)phenyl]-1,3-oxazol-4-yl}methyl)-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-5-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J026-3968

Molecular Formula

C26H28N4O5 (C26 H28 N4 O5)

Compound Name

ethyl 1,7-dimethyl-3-({5-methyl-2-[4-(propan-2-yl)phenyl]-1,3-oxazol-4-yl}methyl)-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-5-carboxylate

IUPAC name

ethyl 17-dimethyl-3-({5-methyl-2-[4-(propan-2-yl)phenyl]-13-oxazol-4-yl}methyl)-24-dioxo-1H2H3H4H-pyrido[23-d]pyrimidine-5-carboxylate

SMILES

CCOC(c1cc(C)nc(N(C)C(N2Cc3c(C)oc(-c4ccc(C(C)C)cc4)n3)=O)c1C2=O)=O

InChI

InChI=1S/C26H28N4O5/c1-7-34-25(32)19-12-15(4)27-22-21(19)24(31)30(26(33)29(22)6)13-20-16(5)35-23(28-20)18-10-8-17(9-11-18)14(2)3/h8-12,14H,7,13H2,1-6H3

InChI Key

RHAMGDWTKSFQMF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD11854636

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

476.53

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

5.117

Distribution Coefficient, logD

5.117

Water Solubility, LogSw

-5.05

Polar Surface Area

79.885

Acid Dissociation Constant (pKa)

23.65

Base Dissociation Constant (pKb)

2.65

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.60

J026-3968 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Antiviral Library (67538 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with J026-3968 chemical compound. It will be published here after verification.

Frequently Asked Questions

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What is the minimum amount of J026-3968 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J026-3968
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J026-3968
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J026-3968 available by request