J026-4074 Screening compound: methyl 7-cyclopropyl-1-methyl-2,4-dioxo-3-[(phenylcarbamoyl)methyl]-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-5-carboxylate

J026-4074 Screening compound: methyl 7-cyclopropyl-1-methyl-2,4-dioxo-3-[(phenylcarbamoyl)methyl]-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-5-carboxylate
J026-4074 Screening compound: methyl 7-cyclopropyl-1-methyl-2,4-dioxo-3-[(phenylcarbamoyl)methyl]-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-5-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound J026-4074
methyl 7-cyclopropyl-1-methyl-2,4-dioxo-3-[(phenylcarbamoyl)methyl]-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-5-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J026-4074

Molecular Formula

C21H20N4O5 (C21 H20 N4 O5)

Compound Name

methyl 7-cyclopropyl-1-methyl-2,4-dioxo-3-[(phenylcarbamoyl)methyl]-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-5-carboxylate

IUPAC name

methyl 7-cyclopropyl-1-methyl-24-dioxo-3-[(phenylcarbamoyl)methyl]-1H2H3H4H-pyrido[23-d]pyrimidine-5-carboxylate

SMILES

CN(c(nc(C1CC1)cc1C(OC)=O)c1C(N1CC(Nc2ccccc2)=O)=O)C1=O

InChI

InChI=1S/C21H20N4O5/c1-24-18-17(14(20(28)30-2)10-15(23-18)12-8-9-12)19(27)25(21(24)29)11-16(26)22-13-6-4-3-5-7-13/h3-7,10,12H,8-9,11H2,1-2H3,(H,22,26)

InChI Key

NGJVGKZXUOEEET-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD12965298

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

408.41

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.845

Distribution Coefficient, logD

2.845

Water Solubility, LogSw

-3.44

Polar Surface Area

85.778

Acid Dissociation Constant (pKa)

13.16

Base Dissociation Constant (pKb)

3.86

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.60

J026-4074 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with J026-4074 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound J026-4074?
Check Price and Availability of J026-4074, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of J026-4074 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J026-4074
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J026-4074
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J026-4074 available by request