J026-4241 Screening compound: 2-[1,7-dimethyl-2,4-dioxo-5-(piperidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]-N-(2-ethylphenyl)acetamide

J026-4241 Screening compound: 2-[1,7-dimethyl-2,4-dioxo-5-(piperidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]-N-(2-ethylphenyl)acetamide
J026-4241 Screening compound: 2-[1,7-dimethyl-2,4-dioxo-5-(piperidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]-N-(2-ethylphenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound J026-4241
2-[1,7-dimethyl-2,4-dioxo-5-(piperidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]-N-(2-ethylphenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J026-4241

Molecular Formula

C25H29N5O4 (C25 H29 N5 O4)

Compound Name

2-[1,7-dimethyl-2,4-dioxo-5-(piperidine-1-carbonyl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-3-yl]-N-(2-ethylphenyl)acetamide

IUPAC name

2-[17-dimethyl-24-dioxo-5-(piperidine-1-carbonyl)-1H2H3H4H-pyrido[23-d]pyrimidin-3-yl]-N-(2-ethylphenyl)acetamide

SMILES

CCc(cccc1)c1NC(CN(C(c1c(N2C)nc(C)cc1C(N1CCCCC1)=O)=O)C2=O)=O

InChI

InChI=1S/C25H29N5O4/c1-4-17-10-6-7-11-19(17)27-20(31)15-30-24(33)21-18(23(32)29-12-8-5-9-13-29)14-16(2)26-22(21)28(3)25(30)34/h6-7,10-11,14H,4-5,8-9,12-13,15H2,1-3H3,(H,27,31)

InChI Key

IBHJVYAQZAUFBS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD11854889

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

463.54

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.993

Distribution Coefficient, logD

2.993

Water Solubility, LogSw

-3.16

Polar Surface Area

80.109

Acid Dissociation Constant (pKa)

13.37

Base Dissociation Constant (pKb)

2.86

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

J026-4241 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Hsp90-Targeted Library (11355 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with J026-4241 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound J026-4241?
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What is the minimum amount of J026-4241 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J026-4241
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J026-4241
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J026-4241 available by request