J029-0298 Screening compound: N-(2-methyl-4-{[1,3]oxazolo[4,5-b]pyridin-2-yl}phenyl)-1-(4-methylphenyl)cyclopentane-1-carboxamide

J029-0298 Screening compound: N-(2-methyl-4-{[1,3]oxazolo[4,5-b]pyridin-2-yl}phenyl)-1-(4-methylphenyl)cyclopentane-1-carboxamide
J029-0298 Screening compound: N-(2-methyl-4-{[1,3]oxazolo[4,5-b]pyridin-2-yl}phenyl)-1-(4-methylphenyl)cyclopentane-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound J029-0298
N-(2-methyl-4-{[1,3]oxazolo[4,5-b]pyridin-2-yl}phenyl)-1-(4-methylphenyl)cyclopentane-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J029-0298

Molecular Formula

C26H25N3O2 (C26 H25 N3 O2)

Compound Name

N-(2-methyl-4-{[1,3]oxazolo[4,5-b]pyridin-2-yl}phenyl)-1-(4-methylphenyl)cyclopentane-1-carboxamide

IUPAC name

N-(2-methyl-4-{[13]oxazolo[45-b]pyridin-2-yl}phenyl)-1-(4-methylphenyl)cyclopentane-1-carboxamide

SMILES

Cc1ccc(C2(CCCC2)C(Nc(cc2)c(C)cc2-c2nc(nccc3)c3o2)=O)cc1

InChI

InChI=1S/C26H25N3O2/c1-17-7-10-20(11-8-17)26(13-3-4-14-26)25(30)28-21-12-9-19(16-18(21)2)24-29-23-22(31-24)6-5-15-27-23/h5-12,15-16H,3-4,13-14H2,1-2H3,(H,28,30)

InChI Key

AMKHAZLREOBYAY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD11855565

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

411.5

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.463

Distribution Coefficient, logD

5.463

Water Solubility, LogSw

-5.20

Polar Surface Area

50.103

Acid Dissociation Constant (pKa)

11.39

Base Dissociation Constant (pKb)

1.77

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.90

J029-0298 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with J029-0298 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound J029-0298?
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What is the minimum amount of J029-0298 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J029-0298
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J029-0298
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J029-0298 available by request