J052-0850 Screening compound: N-(4-chlorophenyl)-3-(4-fluorophenyl)-[1,2,4]triazolo[4,3-a]pyridine-8-carboxamide

J052-0850 Screening compound: N-(4-chlorophenyl)-3-(4-fluorophenyl)-[1,2,4]triazolo[4,3-a]pyridine-8-carboxamide
J052-0850 Screening compound: N-(4-chlorophenyl)-3-(4-fluorophenyl)-[1,2,4]triazolo[4,3-a]pyridine-8-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound J052-0850
N-(4-chlorophenyl)-3-(4-fluorophenyl)-[1,2,4]triazolo[4,3-a]pyridine-8-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J052-0850

Molecular Formula

C19H12ClFN4O (C19 H12 ClFN4 O)

Compound Name

N-(4-chlorophenyl)-3-(4-fluorophenyl)-[1,2,4]triazolo[4,3-a]pyridine-8-carboxamide

IUPAC name

N-(4-chlorophenyl)-3-(4-fluorophenyl)-[124]triazolo[43-a]pyridine-8-carboxamide

SMILES

O=C(c1cccn2c1nnc2-c(cc1)ccc1F)Nc(cc1)ccc1Cl

InChI

InChI=1S/C19H12ClFN4O/c20-13-5-9-15(10-6-13)22-19(26)16-2-1-11-25-17(23-24-18(16)25)12-3-7-14(21)8-4-12/h1-11H,(H,22,26)

InChI Key

QEUIZGTXHIWDCH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27222567

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

366.78

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.822

Distribution Coefficient, logD

3.821

Water Solubility, LogSw

-4.66

Polar Surface Area

45.215

Acid Dissociation Constant (pKa)

10.22

Base Dissociation Constant (pKb)

-1.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

J052-0850 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with J052-0850 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound J052-0850?
Check Price and Availability of J052-0850, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of J052-0850 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J052-0850
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J052-0850
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J052-0850 available by request