J052-1174 Screening compound: 3-(2-fluorophenyl)-N-(prop-2-en-1-yl)-[1,2,4]triazolo[4,3-a]pyridine-8-carboxamide

J052-1174 Screening compound: 3-(2-fluorophenyl)-N-(prop-2-en-1-yl)-[1,2,4]triazolo[4,3-a]pyridine-8-carboxamide
J052-1174 Screening compound: 3-(2-fluorophenyl)-N-(prop-2-en-1-yl)-[1,2,4]triazolo[4,3-a]pyridine-8-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound J052-1174
3-(2-fluorophenyl)-N-(prop-2-en-1-yl)-[1,2,4]triazolo[4,3-a]pyridine-8-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J052-1174

Molecular Formula

C16H13FN4O (C16 H13 FN4 O)

Compound Name

3-(2-fluorophenyl)-N-(prop-2-en-1-yl)-[1,2,4]triazolo[4,3-a]pyridine-8-carboxamide

IUPAC name

3-(2-fluorophenyl)-N-(prop-2-en-1-yl)-[124]triazolo[43-a]pyridine-8-carboxamide

SMILES

C=CCNC(c1cccn2c(-c(cccc3)c3F)nnc12)=O

InChI

InChI=1S/C16H13FN4O/c1-2-9-18-16(22)12-7-5-10-21-14(19-20-15(12)21)11-6-3-4-8-13(11)17/h2-8,10H,1,9H2,(H,18,22)

InChI Key

WCMCFTRKYPUJIB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27222574

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

296.3

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

1.764

Distribution Coefficient, logD

1.764

Water Solubility, LogSw

-2.36

Polar Surface Area

46.650

Acid Dissociation Constant (pKa)

13.18

Base Dissociation Constant (pKb)

3.11

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

6.30

J052-1174 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with J052-1174 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound J052-1174?
Check Price and Availability of J052-1174, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of J052-1174 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J052-1174
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J052-1174
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J052-1174 available by request