J052-1926 Screening compound: N-(4-chloro-2-hydroxyphenyl)-3-(2-fluorophenyl)-[1,2,4]triazolo[4,3-a]pyridine-8-carboxamide

J052-1926 Screening compound: N-(4-chloro-2-hydroxyphenyl)-3-(2-fluorophenyl)-[1,2,4]triazolo[4,3-a]pyridine-8-carboxamide
J052-1926 Screening compound: N-(4-chloro-2-hydroxyphenyl)-3-(2-fluorophenyl)-[1,2,4]triazolo[4,3-a]pyridine-8-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound J052-1926
N-(4-chloro-2-hydroxyphenyl)-3-(2-fluorophenyl)-[1,2,4]triazolo[4,3-a]pyridine-8-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J052-1926

Molecular Formula

C19H12ClFN4O2 (C19 H12 ClFN4 O2)

Compound Name

N-(4-chloro-2-hydroxyphenyl)-3-(2-fluorophenyl)-[1,2,4]triazolo[4,3-a]pyridine-8-carboxamide

IUPAC name

N-(4-chloro-2-hydroxyphenyl)-3-(2-fluorophenyl)-[124]triazolo[43-a]pyridine-8-carboxamide

SMILES

Oc(cc(cc1)Cl)c1NC(c1cccn2c(-c(cccc3)c3F)nnc12)=O

InChI

InChI=1S/C19H12ClFN4O2/c20-11-7-8-15(16(26)10-11)22-19(27)13-5-3-9-25-17(23-24-18(13)25)12-4-1-2-6-14(12)21/h1-10,26H,(H,22,27)

InChI Key

IVIRLWIHZWBULB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27222587

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

382.78

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.262

Distribution Coefficient, logD

3.169

Water Solubility, LogSw

-3.79

Polar Surface Area

61.065

Acid Dissociation Constant (pKa)

8.02

Base Dissociation Constant (pKb)

-1.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

J052-1926 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Hsp90-Targeted Library (11355 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Targets:
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with J052-1926 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound J052-1926?
Check Price and Availability of J052-1926, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of J052-1926 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J052-1926
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J052-1926
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J052-1926 available by request