J059-0220 Screening compound: N-[2-(4-{[(2-fluorophenyl)carbamoyl]methyl}-3-oxo-3,4-dihydroquinoxalin-2-yl)phenyl]-2-methylpropanamide

J059-0220 Screening compound: N-[2-(4-{[(2-fluorophenyl)carbamoyl]methyl}-3-oxo-3,4-dihydroquinoxalin-2-yl)phenyl]-2-methylpropanamide
J059-0220 Screening compound: N-[2-(4-{[(2-fluorophenyl)carbamoyl]methyl}-3-oxo-3,4-dihydroquinoxalin-2-yl)phenyl]-2-methylpropanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound J059-0220
N-[2-(4-{[(2-fluorophenyl)carbamoyl]methyl}-3-oxo-3,4-dihydroquinoxalin-2-yl)phenyl]-2-methylpropanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J059-0220

Molecular Formula

C26H23FN4O3 (C26 H23 FN4 O3)

Compound Name

N-[2-(4-{[(2-fluorophenyl)carbamoyl]methyl}-3-oxo-3,4-dihydroquinoxalin-2-yl)phenyl]-2-methylpropanamide

IUPAC name

N-[2-(4-{[(2-fluorophenyl)carbamoyl]methyl}-3-oxo-34-dihydroquinoxalin-2-yl)phenyl]-2-methylpropanamide

SMILES

CC(C)C(Nc(cccc1)c1C1=Nc(cccc2)c2N(CC(Nc(cccc2)c2F)=O)C1=O)=O

InChI

InChI=1S/C26H23FN4O3/c1-16(2)25(33)30-19-11-5-3-9-17(19)24-26(34)31(22-14-8-7-13-21(22)29-24)15-23(32)28-20-12-6-4-10-18(20)27/h3-14,16H,15H2,1-2H3,(H,28,32)(H,30,33)

InChI Key

CAJXVBZJVXSJIC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15079774

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

458.49

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.633

Distribution Coefficient, logD

3.633

Water Solubility, LogSw

-3.94

Polar Surface Area

68.295

Acid Dissociation Constant (pKa)

10.89

Base Dissociation Constant (pKb)

-0.75

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.40

J059-0220 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with J059-0220 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound J059-0220?
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What is the minimum amount of J059-0220 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J059-0220
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J059-0220
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J059-0220 available by request