J065-0873 Screening compound: N-(2,3-dihydro-1H-inden-1-yl)-1-{[5-(4-methylphenyl)-1,2,4-oxadiazol-3-yl]methyl}piperidine-4-carboxamide

J065-0873 Screening compound: N-(2,3-dihydro-1H-inden-1-yl)-1-{[5-(4-methylphenyl)-1,2,4-oxadiazol-3-yl]methyl}piperidine-4-carboxamide
J065-0873 Screening compound: N-(2,3-dihydro-1H-inden-1-yl)-1-{[5-(4-methylphenyl)-1,2,4-oxadiazol-3-yl]methyl}piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound J065-0873
N-(2,3-dihydro-1H-inden-1-yl)-1-{[5-(4-methylphenyl)-1,2,4-oxadiazol-3-yl]methyl}piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J065-0873

Molecular Formula

C25H28N4O2 (C25 H28 N4 O2)

Compound Name

N-(2,3-dihydro-1H-inden-1-yl)-1-{[5-(4-methylphenyl)-1,2,4-oxadiazol-3-yl]methyl}piperidine-4-carboxamide

IUPAC name

N-(23-dihydro-1H-inden-1-yl)-1-{[5-(4-methylphenyl)-124-oxadiazol-3-yl]methyl}piperidine-4-carboxamide

SMILES

Cc(cc1)ccc1-c1nc(CN(CC2)CCC2C(NC(CC2)c3c2cccc3)=O)no1

InChI

InChI=1S/C25H28N4O2/c1-17-6-8-20(9-7-17)25-27-23(28-31-25)16-29-14-12-19(13-15-29)24(30)26-22-11-10-18-4-2-3-5-21(18)22/h2-9,19,22H,10-16H2,1H3,(H,26,30)/t22-/m0/s1

InChI Key

HFXUJYKCKOCETA-QFIPXVFZSA-N

MDL Number (MFCD)

MFCD27223246

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

416.52

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.858

Distribution Coefficient, logD

3.838

Water Solubility, LogSw

-3.83

Polar Surface Area

61.262

Acid Dissociation Constant (pKa)

12.08

Base Dissociation Constant (pKb)

6.06

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

40.00

J065-0873 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CORONAVIRUS Library (20774 compounds)

GPCR Targeted Library (31838 compounds)

PLpro Library (6343 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with J065-0873 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound J065-0873?
Check Price and Availability of J065-0873, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of J065-0873 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J065-0873
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J065-0873
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J065-0873 available by request