J065-0875 Screening compound: N-(2,3-dihydro-1H-inden-1-yl)-1-{[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-yl]methyl}piperidine-4-carboxamide

J065-0875 Screening compound: N-(2,3-dihydro-1H-inden-1-yl)-1-{[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-yl]methyl}piperidine-4-carboxamide
J065-0875 Screening compound: N-(2,3-dihydro-1H-inden-1-yl)-1-{[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-yl]methyl}piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound J065-0875
N-(2,3-dihydro-1H-inden-1-yl)-1-{[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-yl]methyl}piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J065-0875

Molecular Formula

C24H25FN4O2 (C24 H25 FN4 O2)

Compound Name

N-(2,3-dihydro-1H-inden-1-yl)-1-{[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-yl]methyl}piperidine-4-carboxamide

IUPAC name

N-(23-dihydro-1H-inden-1-yl)-1-{[5-(4-fluorophenyl)-124-oxadiazol-3-yl]methyl}piperidine-4-carboxamide

SMILES

O=C(C1CCN(Cc2noc(-c(cc3)ccc3F)n2)CC1)NC(CC1)c2c1cccc2

InChI

InChI=1S/C24H25FN4O2/c25-19-8-5-18(6-9-19)24-27-22(28-31-24)15-29-13-11-17(12-14-29)23(30)26-21-10-7-16-3-1-2-4-20(16)21/h1-6,8-9,17,21H,7,10-15H2,(H,26,30)/t21-/m0/s1

InChI Key

GCKMNLPHDUKDRR-NRFANRHFSA-N

MDL Number (MFCD)

MFCD15079922

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

420.49

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.464

Distribution Coefficient, logD

3.444

Water Solubility, LogSw

-3.42

Polar Surface Area

61.262

Acid Dissociation Constant (pKa)

12.08

Base Dissociation Constant (pKb)

6.06

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

37.50

J065-0875 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with J065-0875 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound J065-0875?
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What is the minimum amount of J065-0875 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J065-0875
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J065-0875
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J065-0875 available by request