J065-2488 Screening compound: N-(4-hydroxyphenyl)-1-{[5-(4-methylphenyl)-1,2,4-oxadiazol-3-yl]methyl}piperidine-3-carboxamide

J065-2488 Screening compound: N-(4-hydroxyphenyl)-1-{[5-(4-methylphenyl)-1,2,4-oxadiazol-3-yl]methyl}piperidine-3-carboxamide
J065-2488 Screening compound: N-(4-hydroxyphenyl)-1-{[5-(4-methylphenyl)-1,2,4-oxadiazol-3-yl]methyl}piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound J065-2488
N-(4-hydroxyphenyl)-1-{[5-(4-methylphenyl)-1,2,4-oxadiazol-3-yl]methyl}piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J065-2488

Molecular Formula

C22H24N4O3 (C22 H24 N4 O3)

Compound Name

N-(4-hydroxyphenyl)-1-{[5-(4-methylphenyl)-1,2,4-oxadiazol-3-yl]methyl}piperidine-3-carboxamide

IUPAC name

N-(4-hydroxyphenyl)-1-{[5-(4-methylphenyl)-124-oxadiazol-3-yl]methyl}piperidine-3-carboxamide

SMILES

Cc(cc1)ccc1-c1nc(CN(CCC2)CC2C(Nc(cc2)ccc2O)=O)no1

InChI

InChI=1S/C22H24N4O3/c1-15-4-6-16(7-5-15)22-24-20(25-29-22)14-26-12-2-3-17(13-26)21(28)23-18-8-10-19(27)11-9-18/h4-11,17,27H,2-3,12-14H2,1H3,(H,23,28)/t17-/m0/s1

InChI Key

RDUQYHWVTPUAQO-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD27223289

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

392.46

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.865

Distribution Coefficient, logD

2.864

Water Solubility, LogSw

-3.17

Polar Surface Area

77.281

Acid Dissociation Constant (pKa)

10.11

Base Dissociation Constant (pKb)

3.56

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

31.80

J065-2488 in Drug Discovery

Included in Screening Libraries

Hsp90-Targeted Library (11355 compounds)

Covalent Inhibitors Library (7986 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Structure:
  • Cyclic compounds
  • 3D
  • Fragments

References: we are preparing a list of scientific research reports with J065-2488 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound J065-2488?
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What is the minimum amount of J065-2488 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J065-2488
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J065-2488
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J065-2488 available by request