J092-0007 Screening compound: 3-(2-amino-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)-3-hydroxy-2,3-dihydro-1H-indol-2-one

J092-0007 Screening compound: 3-(2-amino-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)-3-hydroxy-2,3-dihydro-1H-indol-2-one
J092-0007 Screening compound: 3-(2-amino-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)-3-hydroxy-2,3-dihydro-1H-indol-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound J092-0007
3-(2-amino-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)-3-hydroxy-2,3-dihydro-1H-indol-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J092-0007

Molecular Formula

C11H9N3O3S (C11 H9 N3 O3 S)

Compound Name

3-(2-amino-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)-3-hydroxy-2,3-dihydro-1H-indol-2-one

IUPAC name

3-(2-amino-4-oxo-45-dihydro-13-thiazol-5-yl)-3-hydroxy-23-dihydro-1H-indol-2-one

SMILES

NC(SC1C(c(cccc2)c2N2)(C2=O)O)=NC1=O

InChI

InChI=1S/C11H9N3O3S/c12-10-14-8(15)7(18-10)11(17)5-3-1-2-4-6(5)13-9(11)16/h1-4,7,17H,(H,13,16)(H2,12,14,15)

InChI Key

VDRMAROPOXATEN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09222209

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

263.28

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

4.00

Rotatable Bond Count

1.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

-0.200

Distribution Coefficient, logD

-0.200

Water Solubility, LogSw

-2.26

Polar Surface Area

82.941

Acid Dissociation Constant (pKa)

11.25

Base Dissociation Constant (pKb)

0.28

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

18.20

J092-0007 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Cardiovascular Library (22201 compounds)

GPCR Targeted Library (31838 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cardiovascular
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with J092-0007 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound J092-0007?
Check Price and Availability of J092-0007, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of J092-0007 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J092-0007
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J092-0007
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J092-0007 available by request