J092-0013 Screening compound: 3-(2-amino-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)-5-fluoro-3-hydroxy-2,3-dihydro-1H-indol-2-one

J092-0013 Screening compound: 3-(2-amino-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)-5-fluoro-3-hydroxy-2,3-dihydro-1H-indol-2-one
J092-0013 Screening compound: 3-(2-amino-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)-5-fluoro-3-hydroxy-2,3-dihydro-1H-indol-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound J092-0013
3-(2-amino-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)-5-fluoro-3-hydroxy-2,3-dihydro-1H-indol-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J092-0013

Molecular Formula

C11H8FN3O3S (C11 H8 FN3 O3 S)

Compound Name

3-(2-amino-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)-5-fluoro-3-hydroxy-2,3-dihydro-1H-indol-2-one

IUPAC name

3-(2-amino-4-oxo-45-dihydro-13-thiazol-5-yl)-5-fluoro-3-hydroxy-23-dihydro-1H-indol-2-one

SMILES

NC(SC1C(c(cc(cc2)F)c2N2)(C2=O)O)=NC1=O

InChI

InChI=1S/C11H8FN3O3S/c12-4-1-2-6-5(3-4)11(18,9(17)14-6)7-8(16)15-10(13)19-7/h1-3,7,18H,(H,14,17)(H2,13,15,16)

InChI Key

KRLMUUNNUDFOJZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09222284

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

281.27

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

4.00

Rotatable Bond Count

1.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

0.083

Distribution Coefficient, logD

0.082

Water Solubility, LogSw

-2.39

Polar Surface Area

82.941

Acid Dissociation Constant (pKa)

10.01

Base Dissociation Constant (pKb)

0.28

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

18.20

J092-0013 in Drug Discovery

Included in Screening Libraries

Anti-infective Library (19449 compounds)

Antiviral Library (67538 compounds)

KRAS-Targeted Library (16000 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

STING Agonist Library (5895 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

New Agro Library (44492 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Immune system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
  • Kinases
  • Others
  • Kinases
Agro:
  • Agro
Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with J092-0013 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound J092-0013?
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What is the minimum amount of J092-0013 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J092-0013
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J092-0013
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J092-0013 available by request