J106-0079 Screening compound: 1-(1H-indazol-3-yl)-5-oxo-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide

J106-0079 Screening compound: 1-(1H-indazol-3-yl)-5-oxo-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide
J106-0079 Screening compound: 1-(1H-indazol-3-yl)-5-oxo-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound J106-0079
1-(1H-indazol-3-yl)-5-oxo-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J106-0079

Molecular Formula

C15H13N5O2S (C15 H13 N5 O2 S)

Compound Name

1-(1H-indazol-3-yl)-5-oxo-N-(1,3-thiazol-2-yl)pyrrolidine-3-carboxamide

IUPAC name

1-(1H-indazol-3-yl)-5-oxo-N-(13-thiazol-2-yl)pyrrolidine-3-carboxamide

SMILES

O=C(C(CC1=O)CN1c1n[nH]c2c1cccc2)Nc1nccs1

InChI

InChI=1S/C15H13N5O2S/c21-12-7-9(14(22)17-15-16-5-6-23-15)8-20(12)13-10-3-1-2-4-11(10)18-19-13/h1-6,9H,7-8H2,(H,18,19)(H,16,17,22)/t9-/m0/s1

InChI Key

ZDGKVEURIKVMAM-VIFPVBQESA-N

MDL Number (MFCD)

MFCD23139210

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

327.37

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.625

Distribution Coefficient, logD

1.615

Water Solubility, LogSw

-2.37

Polar Surface Area

72.967

Acid Dissociation Constant (pKa)

9.05

Base Dissociation Constant (pKb)

1.17

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

20.00

J106-0079 in Drug Discovery

Included in Screening Libraries

Chelators targeting matrix metalloproteinases library (8930 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with J106-0079 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound J106-0079?
Check Price and Availability of J106-0079, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of J106-0079 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J106-0079
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J106-0079
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J106-0079 available by request