J106-0105 Screening compound: 1-(6-BROMO-1H-INDAZOL-3-YL)-5-OXO-N-[2-(PYRIDIN-2-YL)ETHYL]PYRROLIDINE-3-CARBOXAMIDE

J106-0105 Screening compound: 1-(6-BROMO-1H-INDAZOL-3-YL)-5-OXO-N-[2-(PYRIDIN-2-YL)ETHYL]PYRROLIDINE-3-CARBOXAMIDE
J106-0105 Screening compound: 1-(6-BROMO-1H-INDAZOL-3-YL)-5-OXO-N-[2-(PYRIDIN-2-YL)ETHYL]PYRROLIDINE-3-CARBOXAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound J106-0105
1-(6-BROMO-1H-INDAZOL-3-YL)-5-OXO-N-[2-(PYRIDIN-2-YL)ETHYL]PYRROLIDINE-3-CARBOXAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J106-0105

Molecular Formula

C19H18BrN5O2 (C19 H18 BrN5 O2)

Compound Name

1-(6-BROMO-1H-INDAZOL-3-YL)-5-OXO-N-[2-(PYRIDIN-2-YL)ETHYL]PYRROLIDINE-3-CARBOXAMIDE

IUPAC name

n/a

SMILES

O=C(C(CC1=O)CN1c1n[nH]c2c1ccc(Br)c2)NCCc1ncccc1

InChI

InChI=1S/C19H18BrN5O2/c20-13-4-5-15-16(10-13)23-24-18(15)25-11-12(9-17(25)26)19(27)22-8-6-14-3-1-2-7-21-14/h1-5,7,10,12H,6,8-9,11H2,(H,22,27)(H,23,24)/t12-/m1/s1

InChI Key

KIPLXXGKBRAGSE-GFCCVEGCSA-N

MDL Number (MFCD)

MFCD23139282

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

428.29

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.162

Distribution Coefficient, logD

2.157

Water Solubility, LogSw

-2.82

Polar Surface Area

73.196

Acid Dissociation Constant (pKa)

12.33

Base Dissociation Constant (pKb)

5.45

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

26.30

J106-0105 in Drug Discovery

Included in Screening Libraries

Chelators targeting matrix metalloproteinases library (8930 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
  • Antiviral
  • Infections
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with J106-0105 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound J106-0105?
Check Price and Availability of J106-0105, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of J106-0105 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J106-0105
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J106-0105
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J106-0105 available by request