J106-0212 Screening compound: N-[2-(2-FURYL)ETHYL]-1-(1H-INDAZOL-3-YL)-5-OXO-3-PYRROLIDINECARBOXAMIDE

J106-0212 Screening compound: N-[2-(2-FURYL)ETHYL]-1-(1H-INDAZOL-3-YL)-5-OXO-3-PYRROLIDINECARBOXAMIDE
J106-0212 Screening compound: N-[2-(2-FURYL)ETHYL]-1-(1H-INDAZOL-3-YL)-5-OXO-3-PYRROLIDINECARBOXAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound J106-0212
N-[2-(2-FURYL)ETHYL]-1-(1H-INDAZOL-3-YL)-5-OXO-3-PYRROLIDINECARBOXAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J106-0212

Molecular Formula

C18H18N4O3 (C18 H18 N4 O3)

Compound Name

N-[2-(2-FURYL)ETHYL]-1-(1H-INDAZOL-3-YL)-5-OXO-3-PYRROLIDINECARBOXAMIDE

IUPAC name

n/a

SMILES

O=C(C(CC1=O)CN1c1n[nH]c2c1cccc2)NCCc1ccco1

InChI

InChI=1S/C18H18N4O3/c23-16-10-12(18(24)19-8-7-13-4-3-9-25-13)11-22(16)17-14-5-1-2-6-15(14)20-21-17/h1-6,9,12H,7-8,10-11H2,(H,19,24)(H,20,21)/t12-/m1/s1

InChI Key

RFKIMMHJYOUGRW-GFCCVEGCSA-N

MDL Number (MFCD)

MFCD23140104

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

338.37

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.705

Distribution Coefficient, logD

1.705

Water Solubility, LogSw

-1.98

Polar Surface Area

71.401

Acid Dissociation Constant (pKa)

12.33

Base Dissociation Constant (pKb)

-1.73

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

27.80

J106-0212 in Drug Discovery

Included in Screening Libraries

Chelators targeting matrix metalloproteinases library (8930 compounds)

GPCR Targeted Library (31838 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Antiviral
  • Infections
  • Immune system
Targets:
  • Proteases
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with J106-0212 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound J106-0212?
Check Price and Availability of J106-0212, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of J106-0212 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J106-0212
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J106-0212
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J106-0212 available by request