J107-0805 Screening compound: N-(8-chloro-2,3,4,9-tetrahydro-1H-carbazol-1-yl)-3-[(pyrazin-2-yl)formamido]propanamide

J107-0805 Screening compound: N-(8-chloro-2,3,4,9-tetrahydro-1H-carbazol-1-yl)-3-[(pyrazin-2-yl)formamido]propanamide
J107-0805 Screening compound: N-(8-chloro-2,3,4,9-tetrahydro-1H-carbazol-1-yl)-3-[(pyrazin-2-yl)formamido]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound J107-0805
N-(8-chloro-2,3,4,9-tetrahydro-1H-carbazol-1-yl)-3-[(pyrazin-2-yl)formamido]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J107-0805

Molecular Formula

C20H20ClN5O2 (C20 H20 ClN5 O2)

Compound Name

N-(8-chloro-2,3,4,9-tetrahydro-1H-carbazol-1-yl)-3-[(pyrazin-2-yl)formamido]propanamide

IUPAC name

N-(8-chloro-2349-tetrahydro-1H-carbazol-1-yl)-3-[(pyrazin-2-yl)formamido]propanamide

SMILES

O=C(CCNC(c1nccnc1)=O)NC(CCC1)c2c1c1cccc(Cl)c1[nH]2

InChI

InChI=1S/C20H20ClN5O2/c21-14-5-1-3-12-13-4-2-6-15(19(13)26-18(12)14)25-17(27)7-8-24-20(28)16-11-22-9-10-23-16/h1,3,5,9-11,15,26H,2,4,6-8H2,(H,24,28)(H,25,27)/t15-/m0/s1

InChI Key

NYZWQTJFCWFDOY-HNNXBMFYSA-N

MDL Number (MFCD)

MFCD28056760

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

397.86

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.931

Distribution Coefficient, logD

1.931

Water Solubility, LogSw

-2.50

Polar Surface Area

78.355

Acid Dissociation Constant (pKa)

11.67

Base Dissociation Constant (pKb)

-0.45

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

30.00

J107-0805 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

DGK Inhibitors Library (10558 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with J107-0805 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound J107-0805?
Check Price and Availability of J107-0805, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of J107-0805 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J107-0805
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J107-0805
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J107-0805 available by request