J108-0481 Screening compound: 4-[2-(thiophen-2-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]pyridine

J108-0481 Screening compound: 4-[2-(thiophen-2-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]pyridine
J108-0481 Screening compound: 4-[2-(thiophen-2-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]pyridine alternative view

Chemical Structure Depiction of ChemDiv screening compound J108-0481
4-[2-(thiophen-2-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]pyridine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J108-0481

Molecular Formula

C14H9N5S (C14 H9 N5 S)

Compound Name

4-[2-(thiophen-2-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]pyridine

IUPAC name

4-[2-(thiophen-2-yl)-[124]triazolo[15-a]pyrimidin-7-yl]pyridine

SMILES

c1csc(-c2nn3c(-c4ccncc4)ccnc3n2)c1

InChI

InChI=1S/C14H9N5S/c1-2-12(20-9-1)13-17-14-16-8-5-11(19(14)18-13)10-3-6-15-7-4-10/h1-9H

InChI Key

CASRYTSLZGQSSY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD26114848

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

279.33

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.342

Distribution Coefficient, logD

2.342

Water Solubility, LogSw

-2.16

Polar Surface Area

40.388

Acid Dissociation Constant (pKa)

14.00

Base Dissociation Constant (pKb)

4.45

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

J108-0481 in Drug Discovery

Included in Screening Libraries

Bcl2-PPI Inhibitors Library (12246 compounds)

Fragments Library (11262 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
Mechanism of action:
  • PPI modulators
Structure:
  • Fragments

References: we are preparing a list of scientific research reports with J108-0481 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound J108-0481?
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What is the minimum amount of J108-0481 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J108-0481
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J108-0481
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J108-0481 available by request