J500-0389 Screening compound: N~4~-isopropyl-2-[(1-methyl-1H-imidazol-4-yl)carbonyl]-2-azaspiro[4.4]nonane-4-carboxamide

J500-0389 Screening compound: N~4~-isopropyl-2-[(1-methyl-1H-imidazol-4-yl)carbonyl]-2-azaspiro[4.4]nonane-4-carboxamide
J500-0389 Screening compound: N~4~-isopropyl-2-[(1-methyl-1H-imidazol-4-yl)carbonyl]-2-azaspiro[4.4]nonane-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound J500-0389
N~4~-isopropyl-2-[(1-methyl-1H-imidazol-4-yl)carbonyl]-2-azaspiro[4.4]nonane-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

J500-0389

Molecular Formula

C17H26N4O2 (C17 H26 N4 O2)

Compound Name

N~4~-isopropyl-2-[(1-methyl-1H-imidazol-4-yl)carbonyl]-2-azaspiro[4.4]nonane-4-carboxamide

IUPAC name

2-(1-methyl-1H-imidazole-4-carbonyl)-N-(propan-2-yl)-2-azaspiro[4.4]nonane-4-carboxamide

SMILES

CC(C)NC(C(C1)C2(CCCC2)CN1C(c1cn(C)cn1)=O)=O

InChI

InChI=1S/C17H26N4O2/c1-12(2)19-15(22)13-8-21(10-17(13)6-4-5-7-17)16(23)14-9-20(3)11-18-14/h9,11-13H,4-8,10H2,1-3H3,(H,19,22)/t13-/m0/s1

InChI Key

CNSAMGRYVUONIN-ZDUSSCGKSA-N

MDL Number (MFCD)

MFCD32223969

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

318.42

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

0.614

Distribution Coefficient, logD

0.614

Water Solubility, LogSw

-1.58

Polar Surface Area

53.702

Acid Dissociation Constant (pKa)

14.43

Base Dissociation Constant (pKb)

2.63

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

70.59

J500-0389 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

CNS Targets (44014 compounds)

Ion Channels Focused Library (26372 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with J500-0389 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound J500-0389?
Check Price and Availability of J500-0389, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of J500-0389 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for J500-0389
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for J500-0389
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of J500-0389 available by request