K017-0105 Screening compound: (3E)-3-[2-(3-chloro-4-fluorophenyl)hydrazin-1-ylidene]-2,3-dihydro-1H-indol-2-one

K017-0105 Screening compound: (3E)-3-[2-(3-chloro-4-fluorophenyl)hydrazin-1-ylidene]-2,3-dihydro-1H-indol-2-one
K017-0105 Screening compound: (3E)-3-[2-(3-chloro-4-fluorophenyl)hydrazin-1-ylidene]-2,3-dihydro-1H-indol-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound K017-0105
(3E)-3-[2-(3-chloro-4-fluorophenyl)hydrazin-1-ylidene]-2,3-dihydro-1H-indol-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K017-0105

Molecular Formula

C14H9ClFN3O (C14 H9 ClFN3 O)

Compound Name

(3E)-3-[2-(3-chloro-4-fluorophenyl)hydrazin-1-ylidene]-2,3-dihydro-1H-indol-2-one

IUPAC name

(3E)-3-[2-(3-chloro-4-fluorophenyl)hydrazin-1-ylidene]-23-dihydro-1H-indol-2-one

SMILES

O=C1Nc(cccc2)c2/C1=N\Nc(cc1)cc(Cl)c1F

InChI

InChI=1S/C14H9ClFN3O/c15-10-7-8(5-6-11(10)16)18-19-13-9-3-1-2-4-12(9)17-14(13)20/h1-7,18H,(H,17,19,20)

InChI Key

ZZELZAJXZCTJTL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01248273

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

289.7

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.972

Distribution Coefficient, logD

3.972

Water Solubility, LogSw

-4.42

Polar Surface Area

45.185

Acid Dissociation Constant (pKa)

11.46

Base Dissociation Constant (pKb)

2.00

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

K017-0105 in Drug Discovery

Included in Screening Libraries

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K017-0105 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K017-0105?
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What is the minimum amount of K017-0105 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K017-0105
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K017-0105
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K017-0105 available by request