K061-0245 Screening compound: 1-[3-chloro-5-(thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl]-4-(2-methoxyphenyl)piperazine

K061-0245 Screening compound: 1-[3-chloro-5-(thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl]-4-(2-methoxyphenyl)piperazine
K061-0245 Screening compound: 1-[3-chloro-5-(thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl]-4-(2-methoxyphenyl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound K061-0245
1-[3-chloro-5-(thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl]-4-(2-methoxyphenyl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K061-0245

Molecular Formula

C23H19ClF3N5O2S (C23 H19 ClF3 N5 O2 S)

Compound Name

1-[3-chloro-5-(thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl]-4-(2-methoxyphenyl)piperazine

IUPAC name

1-[3-chloro-5-(thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[15-a]pyrimidine-2-carbonyl]-4-(2-methoxyphenyl)piperazine

SMILES

COc(cccc1)c1N(CC1)CCN1C(c1nn2c(C(F)(F)F)cc(-c3cccs3)nc2c1Cl)=O

InChI

InChI=1S/C23H19ClF3N5O2S/c1-34-16-6-3-2-5-15(16)30-8-10-31(11-9-30)22(33)20-19(24)21-28-14(17-7-4-12-35-17)13-18(23(25,26)27)32(21)29-20/h2-7,12-13H,8-11H2,1H3

InChI Key

PIWFSOICLIOOTO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01010075

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

521.95

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.015

Distribution Coefficient, logD

5.015

Water Solubility, LogSw

-5.21

Polar Surface Area

47.971

Acid Dissociation Constant (pKa)

28.32

Base Dissociation Constant (pKb)

5.56

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.10

K061-0245 in Drug Discovery

Included in Screening Libraries

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with K061-0245 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K061-0245?
Check Price and Availability of K061-0245, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K061-0245 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K061-0245
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K061-0245
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K061-0245 available by request