K061-0875 Screening compound: 5-(4-bromophenyl)-3-chloro-N-(2,4-dimethoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide

K061-0875 Screening compound: 5-(4-bromophenyl)-3-chloro-N-(2,4-dimethoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
K061-0875 Screening compound: 5-(4-bromophenyl)-3-chloro-N-(2,4-dimethoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K061-0875
5-(4-bromophenyl)-3-chloro-N-(2,4-dimethoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K061-0875

Molecular Formula

C22H15BrClF3N4O3 (C22 H15 BrClF3 N4 O3)

Compound Name

5-(4-bromophenyl)-3-chloro-N-(2,4-dimethoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide

IUPAC name

5-(4-bromophenyl)-3-chloro-N-(24-dimethoxyphenyl)-7-(trifluoromethyl)pyrazolo[15-a]pyrimidine-2-carboxamide

SMILES

COc(cc1)cc(OC)c1NC(c1nn2c(C(F)(F)F)cc(-c(cc3)ccc3Br)nc2c1Cl)=O

InChI

InChI=1S/C22H15BrClF3N4O3/c1-33-13-7-8-14(16(9-13)34-2)29-21(32)19-18(24)20-28-15(11-3-5-12(23)6-4-11)10-17(22(25,26)27)31(20)30-19/h3-10H,1-2H3,(H,29,32)

InChI Key

JWTKSCYRDSMCOB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01528391

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

555.74

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

6.362

Distribution Coefficient, logD

6.358

Water Solubility, LogSw

-6.51

Polar Surface Area

57.282

Acid Dissociation Constant (pKa)

9.49

Base Dissociation Constant (pKb)

0.64

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.60

K061-0875 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Antiviral Library (67538 compounds)

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Antiviral
  • Infections
  • Immune system
  • Nervous system
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with K061-0875 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K061-0875?
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What is the minimum amount of K061-0875 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K061-0875
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K061-0875
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K061-0875 available by request