K072-0047 Screening compound: 5,7-dichloro-2-[(2E)-2-{[4-(trifluoromethoxy)phenyl]methylidene}hydrazin-1-yl]quinolin-8-ol

K072-0047 Screening compound: 5,7-dichloro-2-[(2E)-2-{[4-(trifluoromethoxy)phenyl]methylidene}hydrazin-1-yl]quinolin-8-ol
K072-0047 Screening compound: 5,7-dichloro-2-[(2E)-2-{[4-(trifluoromethoxy)phenyl]methylidene}hydrazin-1-yl]quinolin-8-ol alternative view

Chemical Structure Depiction of ChemDiv screening compound K072-0047
5,7-dichloro-2-[(2E)-2-{[4-(trifluoromethoxy)phenyl]methylidene}hydrazin-1-yl]quinolin-8-ol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K072-0047

Molecular Formula

C17H10Cl2F3N3O2 (C17 H10 Cl2 F3 N3 O2)

Compound Name

5,7-dichloro-2-[(2E)-2-{[4-(trifluoromethoxy)phenyl]methylidene}hydrazin-1-yl]quinolin-8-ol

IUPAC name

57-dichloro-2-[(2E)-2-{[4-(trifluoromethoxy)phenyl]methylidene}hydrazin-1-yl]quinolin-8-ol

SMILES

Oc(c1nc(N/N=C/c(cc2)ccc2OC(F)(F)F)ccc1c(Cl)c1)c1Cl

InChI

InChI=1S/C17H10Cl2F3N3O2/c18-12-7-13(19)16(26)15-11(12)5-6-14(24-15)25-23-8-9-1-3-10(4-2-9)27-17(20,21)22/h1-8,26H,(H,24,25)

InChI Key

UYTKLJKLFLMMIF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01248661

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

416.19

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

7.056

Distribution Coefficient, logD

6.802

Water Solubility, LogSw

-6.59

Polar Surface Area

52.460

Acid Dissociation Constant (pKa)

7.51

Base Dissociation Constant (pKb)

5.48

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.90

K072-0047 in Drug Discovery

Included in Screening Libraries

Chelators targeting matrix metalloproteinases library (8930 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with K072-0047 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K072-0047?
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What is the minimum amount of K072-0047 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K072-0047
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K072-0047
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K072-0047 available by request