K205-1570 Screening compound: 2-(4-bromophenyl)-3-(2,4-difluorophenyl)-1,3-thiazolidin-4-one
Chemical Structure Depiction of ChemDiv screening compound K205-1570
2-(4-bromophenyl)-3-(2,4-difluorophenyl)-1,3-thiazolidin-4-one
Available from 1 mg
Formats:
- Glass Vials (4ml Glass Vials VWR #97047-678)
- 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)
Shiptime: 1 week worldwide delivery in most cases
Compound Identifiers
ChemDiv Compound ID
K205-1570
Molecular Formula
C15H10BrF2NOS (C15 H10 BrF2 NOS)
Compound Name
2-(4-bromophenyl)-3-(2,4-difluorophenyl)-1,3-thiazolidin-4-one
IUPAC name
2-(4-bromophenyl)-3-(24-difluorophenyl)-13-thiazolidin-4-one
SMILES
O=C(CSC1c(cc2)ccc2Br)N1c(ccc(F)c1)c1F
InChI Key
MDL Number (MFCD)
Chemical and Physical Properties
Saltdata
n/a
Molecular Weight
370.22
Hydrogen Bond Acceptors Count
3.00
Hydrogen Bond Donors Count
0.00
Rotatable Bond Count
2.00
Number of Nitrogen and Oxygen Atoms
2
Partition Coefficient, logP
4.056
Distribution Coefficient, logD
4.056
Water Solubility, LogSw
-4.26
Polar Surface Area
15.832
Acid Dissociation Constant (pKa)
14.56
Base Dissociation Constant (pKb)
-13.39
Number of Chiral Centers
1.00
Percent sp3 carbon bonding
13.30
K205-1570 in Drug Discovery
Included in Screening Libraries
MDM2-p53 interaction inhibitors Library (21687 compounds)
Included in 1.7M Stock Database
- Cancer
- PPI modulators
References: we are preparing a list of scientific research reports with K205-1570 chemical compound. It will be published here after verification.
Frequently Asked Questions
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Available from 1 mg in Glass Vials or 96-tube racks.
ChemDiv sends parcels with Express services (UPS, WC).
- 1–2 days for small orders
- 2–4 weeks for large selections
- 0.5–50 mg of dry powder sample in single glass vials, custom vials
- DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)