K205-1757 Screening compound: 3-(3-fluorophenyl)-2-(6-nitro-2H-1,3-benzodioxol-5-yl)-1,3-thiazolidin-4-one

K205-1757 Screening compound: 3-(3-fluorophenyl)-2-(6-nitro-2H-1,3-benzodioxol-5-yl)-1,3-thiazolidin-4-one
K205-1757 Screening compound: 3-(3-fluorophenyl)-2-(6-nitro-2H-1,3-benzodioxol-5-yl)-1,3-thiazolidin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound K205-1757
3-(3-fluorophenyl)-2-(6-nitro-2H-1,3-benzodioxol-5-yl)-1,3-thiazolidin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K205-1757

Molecular Formula

C16H11FN2O5S (C16 H11 FN2 O5 S)

Compound Name

3-(3-fluorophenyl)-2-(6-nitro-2H-1,3-benzodioxol-5-yl)-1,3-thiazolidin-4-one

IUPAC name

3-(3-fluorophenyl)-2-(6-nitro-2H-13-benzodioxol-5-yl)-13-thiazolidin-4-one

SMILES

[O-][N+](c1c(C(N2c3cc(F)ccc3)SCC2=O)cc2OCOc2c1)=O

InChI

InChI=1S/C16H11FN2O5S/c17-9-2-1-3-10(4-9)18-15(20)7-25-16(18)11-5-13-14(24-8-23-13)6-12(11)19(21)22/h1-6,16H,7-8H2/t16-/m0/s1

InChI Key

MPCBZVUACSLXLF-INIZCTEOSA-N

MDL Number (MFCD)

MFCD01933427

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

362.34

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.010

Distribution Coefficient, logD

3.010

Water Solubility, LogSw

-3.49

Polar Surface Area

66.329

Acid Dissociation Constant (pKa)

14.40

Base Dissociation Constant (pKb)

-10.94

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

18.80

K205-1757 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with K205-1757 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K205-1757?
Check Price and Availability of K205-1757, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K205-1757 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K205-1757
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K205-1757
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K205-1757 available by request