K219-1450 Screening compound: N-[5-ethyl-4-(thiophen-2-yl)-1,3-thiazol-2-yl]-8-methoxy-2-oxo-2H-chromene-3-carboxamide

K219-1450 Screening compound: N-[5-ethyl-4-(thiophen-2-yl)-1,3-thiazol-2-yl]-8-methoxy-2-oxo-2H-chromene-3-carboxamide
K219-1450 Screening compound: N-[5-ethyl-4-(thiophen-2-yl)-1,3-thiazol-2-yl]-8-methoxy-2-oxo-2H-chromene-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K219-1450
N-[5-ethyl-4-(thiophen-2-yl)-1,3-thiazol-2-yl]-8-methoxy-2-oxo-2H-chromene-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K219-1450

Molecular Formula

C20H16N2O4S2 (C20 H16 N2 O4 S2)

Compound Name

N-[5-ethyl-4-(thiophen-2-yl)-1,3-thiazol-2-yl]-8-methoxy-2-oxo-2H-chromene-3-carboxamide

IUPAC name

N-[5-ethyl-4-(thiophen-2-yl)-13-thiazol-2-yl]-8-methoxy-2-oxo-2H-chromene-3-carboxamide

SMILES

CCc1c(-c2cccs2)nc(NC(C2=Cc(cccc3OC)c3OC2=O)=O)s1

InChI

InChI=1S/C20H16N2O4S2/c1-3-14-16(15-8-5-9-27-15)21-20(28-14)22-18(23)12-10-11-6-4-7-13(25-2)17(11)26-19(12)24/h4-10H,3H2,1-2H3,(H,21,22,23)

InChI Key

UREAZSOTIQKPDG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15081798

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

412.49

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.766

Distribution Coefficient, logD

4.581

Water Solubility, LogSw

-4.59

Polar Surface Area

63.130

Acid Dissociation Constant (pKa)

7.68

Base Dissociation Constant (pKb)

-1.91

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.00

K219-1450 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with K219-1450 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K219-1450?
Check Price and Availability of K219-1450, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K219-1450 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K219-1450
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K219-1450
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K219-1450 available by request