K219-1473 Screening compound: 6-methoxy-2-oxo-N-[4-(4-phenoxyphenyl)-1,3-thiazol-2-yl]-2H-chromene-3-carboxamide

K219-1473 Screening compound: 6-methoxy-2-oxo-N-[4-(4-phenoxyphenyl)-1,3-thiazol-2-yl]-2H-chromene-3-carboxamide
K219-1473 Screening compound: 6-methoxy-2-oxo-N-[4-(4-phenoxyphenyl)-1,3-thiazol-2-yl]-2H-chromene-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K219-1473
6-methoxy-2-oxo-N-[4-(4-phenoxyphenyl)-1,3-thiazol-2-yl]-2H-chromene-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K219-1473

Molecular Formula

C26H18N2O5S (C26 H18 N2 O5 S)

Compound Name

6-methoxy-2-oxo-N-[4-(4-phenoxyphenyl)-1,3-thiazol-2-yl]-2H-chromene-3-carboxamide

IUPAC name

6-methoxy-2-oxo-N-[4-(4-phenoxyphenyl)-13-thiazol-2-yl]-2H-chromene-3-carboxamide

SMILES

COc(cc1)cc(C=C2C(Nc3nc(-c(cc4)ccc4Oc4ccccc4)cs3)=O)c1OC2=O

InChI

InChI=1S/C26H18N2O5S/c1-31-20-11-12-23-17(13-20)14-21(25(30)33-23)24(29)28-26-27-22(15-34-26)16-7-9-19(10-8-16)32-18-5-3-2-4-6-18/h2-15H,1H3,(H,27,28,29)

InChI Key

WZZGZYDHZLRUON-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15081799

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

470.51

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

6.190

Distribution Coefficient, logD

6.177

Water Solubility, LogSw

-5.63

Polar Surface Area

68.318

Acid Dissociation Constant (pKa)

8.93

Base Dissociation Constant (pKb)

-3.78

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

3.80

K219-1473 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Allosteric Kinases Inhibitors Library (23117 compounds)

Anticancer Library (62698 compounds)

Antimitotic Tubulin Library (17355 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K219-1473 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K219-1473?
Check Price and Availability of K219-1473, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K219-1473 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K219-1473
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K219-1473
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K219-1473 available by request