K220-12352 Screening compound: 4-{[(2Z)-3-[(3,5-dimethylphenyl)carbamoyl]-6-methoxy-2H-chromen-2-ylidene]amino}benzoic acid

K220-12352 Screening compound: 4-{[(2Z)-3-[(3,5-dimethylphenyl)carbamoyl]-6-methoxy-2H-chromen-2-ylidene]amino}benzoic acid
K220-12352 Screening compound: 4-{[(2Z)-3-[(3,5-dimethylphenyl)carbamoyl]-6-methoxy-2H-chromen-2-ylidene]amino}benzoic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound K220-12352
4-{[(2Z)-3-[(3,5-dimethylphenyl)carbamoyl]-6-methoxy-2H-chromen-2-ylidene]amino}benzoic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K220-12352

Molecular Formula

C26H22N2O5 (C26 H22 N2 O5)

Compound Name

4-{[(2Z)-3-[(3,5-dimethylphenyl)carbamoyl]-6-methoxy-2H-chromen-2-ylidene]amino}benzoic acid

IUPAC name

4-{[(2Z)-3-[(35-dimethylphenyl)carbamoyl]-6-methoxy-2H-chromen-2-ylidene]amino}benzoic acid

SMILES

Cc1cc(NC(C2=Cc(cc(cc3)OC)c3O/C2=N\c(cc2)ccc2C(O)=O)=O)cc(C)c1

InChI

InChI=1S/C26H22N2O5/c1-15-10-16(2)12-20(11-15)27-24(29)22-14-18-13-21(32-3)8-9-23(18)33-25(22)28-19-6-4-17(5-7-19)26(30)31/h4-14H,1-3H3,(H,27,29)(H,30,31)

InChI Key

GLRIOJHEIAMVQS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15081819

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

442.47

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.974

Distribution Coefficient, logD

1.584

Water Solubility, LogSw

-4.57

Polar Surface Area

74.988

Acid Dissociation Constant (pKa)

4.01

Base Dissociation Constant (pKb)

0.63

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.50

K220-12352 in Drug Discovery

Included in Screening Libraries

RAR (Nuclear receptors) Ligands Library (6524 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Respiratory tract
  • Eye
  • Male
  • Female
  • Hemic and lymphatic
  • Congenital
  • Skin
  • Endocrine
  • Immune system
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K220-12352 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K220-12352?
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What is the minimum amount of K220-12352 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K220-12352
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K220-12352
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K220-12352 available by request