K221-2357 Screening compound: 2-(2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl)-N-{3-[ethyl(3-methylphenyl)amino]propyl}acetamide

K221-2357 Screening compound: 2-(2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl)-N-{3-[ethyl(3-methylphenyl)amino]propyl}acetamide
K221-2357 Screening compound: 2-(2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl)-N-{3-[ethyl(3-methylphenyl)amino]propyl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K221-2357
2-(2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl)-N-{3-[ethyl(3-methylphenyl)amino]propyl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K221-2357

Molecular Formula

C22H26N4O3 (C22 H26 N4 O3)

Compound Name

2-(2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl)-N-{3-[ethyl(3-methylphenyl)amino]propyl}acetamide

IUPAC name

2-(24-dioxo-1234-tetrahydroquinazolin-3-yl)-N-{3-[ethyl(3-methylphenyl)amino]propyl}acetamide

SMILES

CCN(CCCNC(CN(C(c(cccc1)c1N1)=O)C1=O)=O)c1cc(C)ccc1

InChI

InChI=1S/C22H26N4O3/c1-3-25(17-9-6-8-16(2)14-17)13-7-12-23-20(27)15-26-21(28)18-10-4-5-11-19(18)24-22(26)29/h4-6,8-11,14H,3,7,12-13,15H2,1-2H3,(H,23,27)(H,24,29)

InChI Key

VJFWITATCDSOAW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15081869

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

394.47

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.018

Distribution Coefficient, logD

2.985

Water Solubility, LogSw

-3.37

Polar Surface Area

67.783

Acid Dissociation Constant (pKa)

10.40

Base Dissociation Constant (pKb)

6.29

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.80

References: we are preparing a list of scientific research reports with K221-2357 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K221-2357?
Check Price and Availability of K221-2357, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K221-2357 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K221-2357
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K221-2357
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K221-2357 available by request