K221-2429 Screening compound: 6-(2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl)-N-(2-methoxyethyl)hexanamide

K221-2429 Screening compound: 6-(2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl)-N-(2-methoxyethyl)hexanamide
K221-2429 Screening compound: 6-(2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl)-N-(2-methoxyethyl)hexanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K221-2429
6-(2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl)-N-(2-methoxyethyl)hexanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K221-2429

Molecular Formula

C17H23N3O4 (C17 H23 N3 O4)

Compound Name

6-(2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl)-N-(2-methoxyethyl)hexanamide

IUPAC name

6-(24-dioxo-1234-tetrahydroquinazolin-3-yl)-N-(2-methoxyethyl)hexanamide

SMILES

COCCNC(CCCCCN(C(c(cccc1)c1N1)=O)C1=O)=O

InChI

InChI=1S/C17H23N3O4/c1-24-12-10-18-15(21)9-3-2-6-11-20-16(22)13-7-4-5-8-14(13)19-17(20)23/h4-5,7-8H,2-3,6,9-12H2,1H3,(H,18,21)(H,19,23)

InChI Key

LIBXUHIIWOIAQI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15081886

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

333.39

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.326

Distribution Coefficient, logD

1.326

Water Solubility, LogSw

-2.15

Polar Surface Area

73.386

Acid Dissociation Constant (pKa)

10.12

Base Dissociation Constant (pKb)

-0.35

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

47.10

K221-2429 in Drug Discovery

Included in Screening Libraries

Dark Chemical Matter Library (18430 compounds)

KRAS-Targeted Library (16000 compounds)

Included in 1.7M Stock Database

Structure:
  • Pool
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K221-2429 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K221-2429?
Check Price and Availability of K221-2429, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K221-2429 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K221-2429
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K221-2429
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K221-2429 available by request