K227-0331 Screening compound: [(2Z)-8-methyl-3-[(4-methylphenyl)carbamoyl]-2-[(4-phenoxyphenyl)imino]-2H-pyrano[2,3-c]pyridin-5-yl]methyl acetate

K227-0331 Screening compound: [(2Z)-8-methyl-3-[(4-methylphenyl)carbamoyl]-2-[(4-phenoxyphenyl)imino]-2H-pyrano[2,3-c]pyridin-5-yl]methyl acetate
K227-0331 Screening compound: [(2Z)-8-methyl-3-[(4-methylphenyl)carbamoyl]-2-[(4-phenoxyphenyl)imino]-2H-pyrano[2,3-c]pyridin-5-yl]methyl acetate alternative view

Chemical Structure Depiction of ChemDiv screening compound K227-0331
[(2Z)-8-methyl-3-[(4-methylphenyl)carbamoyl]-2-[(4-phenoxyphenyl)imino]-2H-pyrano[2,3-c]pyridin-5-yl]methyl acetate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K227-0331

Molecular Formula

C32H27N3O5 (C32 H27 N3 O5)

Compound Name

[(2Z)-8-methyl-3-[(4-methylphenyl)carbamoyl]-2-[(4-phenoxyphenyl)imino]-2H-pyrano[2,3-c]pyridin-5-yl]methyl acetate

IUPAC name

[(2Z)-8-methyl-3-[(4-methylphenyl)carbamoyl]-2-[(4-phenoxyphenyl)imino]-2H-pyrano[23-c]pyridin-5-yl]methyl acetate

SMILES

CC(OCc1cnc(C)c(O2)c1C=C(C(Nc1ccc(C)cc1)=O)/C2=N/c(cc1)ccc1Oc1ccccc1)=O

InChI

InChI=1S/C32H27N3O5/c1-20-9-11-24(12-10-20)34-31(37)29-17-28-23(19-38-22(3)36)18-33-21(2)30(28)40-32(29)35-25-13-15-27(16-14-25)39-26-7-5-4-6-8-26/h4-18H,19H2,1-3H3,(H,34,37)

InChI Key

CAMCNKMPCDVUAV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03450205

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

533.58

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

5.829

Distribution Coefficient, logD

5.829

Water Solubility, LogSw

-5.44

Polar Surface Area

76.413

Acid Dissociation Constant (pKa)

11.71

Base Dissociation Constant (pKb)

2.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.50

K227-0331 in Drug Discovery

Included in Screening Libraries

MCL1 Targeted Library (12200 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic

References: we are preparing a list of scientific research reports with K227-0331 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K227-0331?
Check Price and Availability of K227-0331, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K227-0331 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K227-0331
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K227-0331
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K227-0331 available by request