K232-1787 Screening compound: N'-[2-(3,4-dimethoxyphenyl)ethyl]-N-[4-(8-methoxy-2-oxo-2H-chromen-3-yl)-1,3-thiazol-2-yl]butanediamide

K232-1787 Screening compound: N'-[2-(3,4-dimethoxyphenyl)ethyl]-N-[4-(8-methoxy-2-oxo-2H-chromen-3-yl)-1,3-thiazol-2-yl]butanediamide
K232-1787 Screening compound: N'-[2-(3,4-dimethoxyphenyl)ethyl]-N-[4-(8-methoxy-2-oxo-2H-chromen-3-yl)-1,3-thiazol-2-yl]butanediamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K232-1787
N'-[2-(3,4-dimethoxyphenyl)ethyl]-N-[4-(8-methoxy-2-oxo-2H-chromen-3-yl)-1,3-thiazol-2-yl]butanediamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K232-1787

Molecular Formula

C27H27N3O7S (C27 H27 N3 O7 S)

Compound Name

N'-[2-(3,4-dimethoxyphenyl)ethyl]-N-[4-(8-methoxy-2-oxo-2H-chromen-3-yl)-1,3-thiazol-2-yl]butanediamide

IUPAC name

N'-[2-(34-dimethoxyphenyl)ethyl]-N-[4-(8-methoxy-2-oxo-2H-chromen-3-yl)-13-thiazol-2-yl]butanediamide

SMILES

COc(ccc(CCNC(CCC(Nc1nc(C2=Cc(cccc3OC)c3OC2=O)cs1)=O)=O)c1)c1OC

InChI

InChI=1S/C27H27N3O7S/c1-34-20-8-7-16(13-22(20)36-3)11-12-28-23(31)9-10-24(32)30-27-29-19(15-38-27)18-14-17-5-4-6-21(35-2)25(17)37-26(18)33/h4-8,13-15H,9-12H2,1-3H3,(H,28,31)(H,29,30,32)

InChI Key

ZNYKHGHKJZVJJG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15083129

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

537.59

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

13.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.213

Distribution Coefficient, logD

2.202

Water Solubility, LogSw

-3.07

Polar Surface Area

100.701

Acid Dissociation Constant (pKa)

8.99

Base Dissociation Constant (pKb)

0.56

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.90

K232-1787 in Drug Discovery

Included in Screening Libraries

Eccentric PPI Library (11937 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with K232-1787 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K232-1787?
Check Price and Availability of K232-1787, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K232-1787 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K232-1787
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K232-1787
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K232-1787 available by request