K242-0294 Screening compound: 2-{[1-(4-methoxyphenyl)-4-(4-methylphenyl)-1H-imidazol-2-yl]sulfanyl}-N-(4-methylphenyl)acetamide

K242-0294 Screening compound: 2-{[1-(4-methoxyphenyl)-4-(4-methylphenyl)-1H-imidazol-2-yl]sulfanyl}-N-(4-methylphenyl)acetamide
K242-0294 Screening compound: 2-{[1-(4-methoxyphenyl)-4-(4-methylphenyl)-1H-imidazol-2-yl]sulfanyl}-N-(4-methylphenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K242-0294
2-{[1-(4-methoxyphenyl)-4-(4-methylphenyl)-1H-imidazol-2-yl]sulfanyl}-N-(4-methylphenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K242-0294

Molecular Formula

C26H25N3O2S (C26 H25 N3 O2 S)

Compound Name

2-{[1-(4-methoxyphenyl)-4-(4-methylphenyl)-1H-imidazol-2-yl]sulfanyl}-N-(4-methylphenyl)acetamide

IUPAC name

2-{[1-(4-methoxyphenyl)-4-(4-methylphenyl)-1H-imidazol-2-yl]sulfanyl}-N-(4-methylphenyl)acetamide

SMILES

Cc(cc1)ccc1-c(nc1SCC(Nc2ccc(C)cc2)=O)cn1-c(cc1)ccc1OC

InChI

InChI=1S/C26H25N3O2S/c1-18-4-8-20(9-5-18)24-16-29(22-12-14-23(31-3)15-13-22)26(28-24)32-17-25(30)27-21-10-6-19(2)7-11-21/h4-16H,17H2,1-3H3,(H,27,30)

InChI Key

MXKOJZQNWLNOCW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15083565

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

443.57

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

6.539

Distribution Coefficient, logD

6.538

Water Solubility, LogSw

-5.51

Polar Surface Area

42.400

Acid Dissociation Constant (pKa)

12.80

Base Dissociation Constant (pKb)

4.05

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.40

K242-0294 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K242-0294 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K242-0294?
Check Price and Availability of K242-0294, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K242-0294 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K242-0294
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K242-0294
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K242-0294 available by request