K243-0143 Screening compound: 3-(2,4-dichlorophenyl)-6-(4-fluorophenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine

K243-0143 Screening compound: 3-(2,4-dichlorophenyl)-6-(4-fluorophenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine
K243-0143 Screening compound: 3-(2,4-dichlorophenyl)-6-(4-fluorophenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine alternative view

Chemical Structure Depiction of ChemDiv screening compound K243-0143
3-(2,4-dichlorophenyl)-6-(4-fluorophenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K243-0143

Molecular Formula

C16H9Cl2FN4S (C16 H9 Cl2 FN4 S)

Compound Name

3-(2,4-dichlorophenyl)-6-(4-fluorophenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine

IUPAC name

3-(24-dichlorophenyl)-6-(4-fluorophenyl)-7H-[124]triazolo[34-b][134]thiadiazine

SMILES

Fc(cc1)ccc1C(CS1)=Nn2c1nnc2-c(ccc(Cl)c1)c1Cl

InChI

InChI=1S/C16H9Cl2FN4S/c17-10-3-6-12(13(18)7-10)15-20-21-16-23(15)22-14(8-24-16)9-1-4-11(19)5-2-9/h1-7H,8H2

InChI Key

XVMWYPXANHPGBF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04009193

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

379.24

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.976

Distribution Coefficient, logD

4.975

Water Solubility, LogSw

-5.41

Polar Surface Area

33.958

Acid Dissociation Constant (pKa)

19.07

Base Dissociation Constant (pKb)

4.44

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

6.30

K243-0143 in Drug Discovery

Included in Screening Libraries

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K243-0143 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K243-0143?
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What is the minimum amount of K243-0143 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K243-0143
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K243-0143
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K243-0143 available by request