K243-0287 Screening compound: 3-(3,4-dichlorophenyl)-6-(3-methoxyphenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine

K243-0287 Screening compound: 3-(3,4-dichlorophenyl)-6-(3-methoxyphenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine
K243-0287 Screening compound: 3-(3,4-dichlorophenyl)-6-(3-methoxyphenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine alternative view

Chemical Structure Depiction of ChemDiv screening compound K243-0287
3-(3,4-dichlorophenyl)-6-(3-methoxyphenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K243-0287

Molecular Formula

C17H12Cl2N4OS (C17 H12 Cl2 N4 OS)

Compound Name

3-(3,4-dichlorophenyl)-6-(3-methoxyphenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine

IUPAC name

3-(34-dichlorophenyl)-6-(3-methoxyphenyl)-7H-[124]triazolo[34-b][134]thiadiazine

SMILES

COc1cccc(C(CS2)=Nn3c2nnc3-c(cc2)cc(Cl)c2Cl)c1

InChI

InChI=1S/C17H12Cl2N4OS/c1-24-12-4-2-3-10(7-12)15-9-25-17-21-20-16(23(17)22-15)11-5-6-13(18)14(19)8-11/h2-8H,9H2,1H3

InChI Key

OSGLFJKJKWLCNR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15083726

Chemical and Physical Properties

Saltdata

HBr

Molecular Weight

391.28

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.313

Distribution Coefficient, logD

5.309

Water Solubility, LogSw

-6.11

Polar Surface Area

41.502

Acid Dissociation Constant (pKa)

19.46

Base Dissociation Constant (pKb)

5.35

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.80

K243-0287 in Drug Discovery

Included in Screening Libraries

CNS BBB Library (22607 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with K243-0287 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K243-0287?
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What is the minimum amount of K243-0287 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K243-0287
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K243-0287
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K243-0287 available by request